Evolution and Genetic Dynamics

Impact of complex spatial population structure on early and long-term adaptation in rugged fitness landscapes

The paper examines how spatial population structure and migration affect adaptation in rugged fitness landscapes, finding that suppression of selection can enhance early adaptation but reduce long-term fitness.

Pre-exposure to stress reduces loss of community and genetic diversity following severe environmental disturbance

The paper shows that pre-exposure to stress increases community and genetic diversity resilience in bacterial communities under severe acidification.

Unprecedented female mutation bias in aye-ayes

This study finds a female mutation bias in aye-ayes, contrasting the typical male mutation bias in mammals, and identifies potential genetic causes.

Experimentally mimicking long term infections of Magallana gigas with the OsHV-1 virus reveals evolution through positive selection

This study investigates OsHV-1 viral evolution in response to oyster host genetic variation, finding genetic homogenization and stronger positive selection in susceptible hosts.

Fecundity-immunity trade-off curvature modulates host evolutionary dynamics, pathogen propagation,and host abundance

This paper models how the curvature of fecundity-immunity trade-offs affects host evolution, pathogen spread, and host abundance using an SIR framework.

Rapid Rescue: Spatial Storage Effect Facilitates Evolutionary Rescue in Rapidly Changing Environments

This study shows that the spatial storage effect enhances population persistence in variable environments by enabling evolutionary rescue, even in small populations with fluctuating sizes.

Disease as a Mediator of Somatic Mutation - Lifespan Coevolution:Model Analysis and Empirical Tests

This paper develops a coevolutionary model linking somatic mutation rate and lifespan, showing it explains empirical relationships and predicts evolutionary responses to disease.

Positive correlations in susceptibility to a diverse panel of viruses across host species

The paper examines phylogenetic correlations in susceptibility to multiple viruses across Drosophilidae hosts and finds positive correlations, with stronger links within viral species and families.

Exaptation and de novo mutations transcend cryptic variations as drivers of adaptation in yeast

This study shows that yeast populations in predictable environments lose adaptive potential, with adaptation to stress driven by de novo mutations rather than pre-existing cryptic variations.

Evolutionary rescue of bacterial populations by heterozygosity on multicopy plasmids

This study analyzes how plasmid-mediated heterozygosity can enable bacterial populations to adapt to stressors through evolutionary rescue, showing that higher plasmid copy numbers lower the fitness threshold needed for rescue.

Metabolic constraints modulate the likelihood and predictability of global epistasis

The paper shows that metabolic constraints influence global epistasis, making fitness effects less predictable as genetic divergence increases.

Evolution of developmental bias explains divergent patterns of phenotypic evolution

The paper quantifies mutational sensitivity in nematode vulval development and shows how differences in sensitivity between clades explain divergent phenotypic evolution patterns.

The number of immune defense and counter-defense systems sustained in the arms race between procaryotes and viruses

The paper argues that the number of defense and counter-defense systems in the prokaryote-virus arms race is limited to around 10 due to metabolic and autoimmune costs.

Evidence of a Slower-Z effect in Schistosoma japonicum

The paper examines the evolutionary dynamics of diploid and hemizygous Z chromosome regions in Schistosoma japonicum, finding reduced efficacy of selection and relaxed purifying selection in diploid Z regions.

More extinction driven by Red Queen in smaller habitats

The paper shows that smaller habitats increase extinction risk in bacterium-virus coevolution, with viruses more likely to go extinct and surviving viruses showing reduced infectivity.

An extreme mutational hotspot in nlpD depends on transcriptional induction of rpoS

The paper identifies a mutational hotspot in nlpD linked to transcriptional induction of rpoS in Pseudomonas fluorescens SBW25, showing a 5,700-fold elevated mutation rate at this site.

The role of asymmetric migration on local adaptation: an analysis of the classic two-habitat migration model

The paper examines how asymmetric migration rates affect local adaptation in a two-habitat model, showing migration can both suppress and facilitate adaptation depending on symmetry.

Plastic responses to past environments shape adaptation to novel selection pressures

This study shows ancestral plasticity to salt helped Silene uniflora adapt to zinc in mine-waste environments, demonstrating past-cue plasticity's role in rapid adaptation to novel habitats.

Evolutionary potential of the Escherichia coli antimutator ΔnudJ is reduced via altered mutational spectrum

This study examines how the antimutator ΔnudJ in Escherichia coli reduces mutation rate and alters mutational spectrum, leading to decreased antibiotic resistance potential.

A cheater founds the winning lineages during evolution of a novel metabolic pathway

The paper evolves a novel metabolic pathway in E. coli by identifying mutations that increase PLP accumulation and reveals a cheater strain's role in lineage dominance.

A generalized structured coalescent for purifying selection without recombination

This study extends the fitness-class coalescent model to account for arbitrary levels of purifying selection, revealing biases in demographic inference caused by selection.

Microbial cross-feeding is stabilized when a dependent mutant is segregated from its independent ancestor

The paper shows that gene-loss mutants can persist in microbial communities when spatially separated from their competitive ancestors, even without a growth rate advantage.

Co-translational assembly promotes functional diversification of paralogous proteins

The paper identifies co-translational assembly as a mechanism promoting homomerization of paralogs, which enhances their functional divergence.

Adaptive evolutionary trajectories in complexity: repeated transitions between unicellularity and differentiated multicellularity

This study uses mathematical models to show that repeated exposure to abiotic stress can lead to adaptive transitions between unicellularity and differentiated multicellularity, with complexity increasing or decreasing depending on mutation order and fitness effects.

Transgressive Hybrids as Hopeful Holobionts

This paper investigates hybridization effects on microbiota in a successful hybrid lizard, finding transgressive segregation of host-associated microbiota traits linked to ecological success.

Dispersal of influenza virus populations within the respiratory tract shapes their evolutionary potential

This study shows that dispersal within the respiratory tract affects viral genetic diversity and evolutionary potential, with nasal and tracheal regions maintaining diversity while lung regions show genetic distinctness.

A putative bacterial ecocline in Klebsiella pneumoniae

The paper identifies a genetic ecocline in Klebsiella pneumoniae using PCA, suggesting diversifying selection on a quantitative trait, with Kpa fimbriae as a potential candidate.

Multilevel gene expression changes inlineages containing adaptive copy numbervariants

The paper examines gene expression changes in yeast strains with adaptive copy-number variants, finding correlations between CNVs and transcript abundance, but reduced proteomic effects due to post-transcriptional compensation.

Measuring the Strength of Spatial Sorting

The paper introduces a quantitative genetics model to measure spatial sorting strength, finding it comparable to natural selection gradients in a soapberry bug recolonization study.

The evolution of mutation rates in the light of development and cell-lineage selection

The paper presents a theoretical framework showing mutation rates are influenced by developmental parameters and intraorganismal selection, not just molecular mutation rates.