Electron Spin Resonance Studies

Revealing essential properties for enhanced quantum sensing in engineered AsLOV2 proteins

The paper analyzes engineered MagLOV variants to understand how mutations affect their magnetic response by examining conformational changes and electron transfer dynamics.

Reconstructing time-resolved inter-residue distance distributions in a protein ensemble during functional dynamics in solution

This paper develops a method to reconstruct time-resolved inter-residue distance distributions in proteins during functional dynamics using rs-TiGGER spectra and applies it to AsLOV2.

The low-field effect in radical pairs: a zero-field singlet-triplet basis picture

This paper presents a new formulation of the low-field effect in radical pairs using a zero-field singlet-triplet basis, revealing the mechanism as a sequential process involving hyperfine and Zeeman interactions.

Optically detected and radio wave-controlled spin chemistry in flavoproteins

This paper demonstrates that flavoproteins like cryptochrome and iLOV exhibit optically detected magnetic resonance, enabling magnetic field sensing and photoluminescence modulation via radiofrequency pulses.

Quantum Spin Resonance in Engineered Magneto-Sensitive Fluorescent Proteins Enables Multi-Modal Sensing in Living Cells

This paper introduces engineered magneto-sensitive fluorescent proteins that enable quantum sensing in living cells through optically detected magnetic resonance.

Development of an EPR-based methodology to study protein-lipid interaction

This paper develops an EPR-based method to quantify protein-lipid interactions, demonstrating its ability to measure binding affinity and concentration of Tau protein with lipids.

Magnetic Resonance Reveals Radical Stability in Native Biofilms and its Role in Bacterial Resistance

This study uses magnetic resonance techniques to show how biofilm structure influences radical stability and bacterial resistance by regulating molecular transport and reactivity.

A High-Sensitivity Stopped-Flow EPR System to Monitor Millisecond Conformational Kinetics in Spin-Labeled Proteins

The paper develops a high-sensitivity stopped-flow EPR system for studying millisecond protein conformational dynamics, demonstrating its use on T4 lysozyme and β2 adrenergic receptor.

Flavoproteins as native and genetically encoded spin probes for in cell ESR spectroscopy

This paper uses ESR spectroscopy to study flavoprotein dynamics in bacterial cells, revealing structural insights and developing a genetically encoded probe for in-cell structural analysis.

Domain-Specific EPR Spectroscopy to Monitor Facilitated Dissociation of a DNA-Transcription Factor Complex

This study uses EPR spectroscopy to analyze the dissociation dynamics of MAX from DNA, revealing domain-specific changes and the impact of BRCA1 on this process.

Improved EPR sensitivity for aqueous biological samples using low-volume multi-channel cells and dielectric resonators

This paper improves EPR sensitivity for small aqueous biological samples using optimized dielectric resonators and multi-channel cells.

An Order of Magnitude Signal-to-Noise Improvement of Magnetic Resonance Spectra using a Segmented-Overlap Fourier-Filtering and Averaging (SOFFA) Approach.

The paper introduces SOFFA, a method improving magnetic resonance spectra signal-to-noise ratio by 5.6-10.3 times across different experiments without increasing acquisition time.

Expanding the diversity of nitroxide-based paramagnetic probes conjugated to non-canonical amino acids for SDSL-EPR applications

This paper introduces new nitroxide labels for SDSL-EPR that target non-canonical amino acids, enhancing the study of protein dynamics and structure.

Identifying the Copper Coordination Environment Between Interacting Neurodegenerative Proteins: A New Approach Using Pulsed EPR with 14N/15N Isotopic Labelling

This paper uses pulsed EPR with 14N/15N isotopic labeling to characterize Cu2+ coordination between PrPC and Aβ, revealing how copper bridges these proteins in a ternary complex.

Localized Reconstruction of Multimodal Distance Distribution from DEER Data of Biopolymers

This paper introduces SF-SVD and WavPDS methods to accurately reconstruct distance distributions from DEER data of biopolymers, resolving broad and mixed features without prior knowledge.

A pressure-jump EPR system to monitor millisecond conformational exchange rates of spin-labeled proteins

The paper introduces a pressure-jump EPR system to measure millisecond conformational exchange rates in spin-labeled proteins and demonstrates its application to T4 lysozyme.