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This study identifies hypersialylation in intervertebral disc degeneration and shows it modulates inflammation and metabolism.

This study shows that ECM viscoelastic properties in bone fracture hematoma influence macrophage polarization, with high stress relaxation time promoting pro-inflammatory and low promoting anti-inflammatory responses.

This paper develops a 3D computational model of microvascular beds and interstitial spaces to better understand fluid flow dynamics and the effects of vascular permeability.

This study identifies temporal mismatch between mRNA delivery and spermatogenesis as a barrier to functional rescue, showing that sustained expression aligned with developmental timing enables recovery in genetic infertility models.

The paper detects Cryptosporidium parvum in invasive beavers in southern Tierra del Fuego, Chile, highlighting their potential role as zoonotic pathogen reservoirs.

This study evaluates a dual-wavelength, polarization-sensitive PPG sensor across different skin tones, finding that cross-polarization improves perfusion index measurements, particularly for darker skin tones.

This study investigates bacterial microcompartment shell proteins as photovoltaic materials, showing their semiconducting properties and efficient electron transfer under UV light.

This study investigates the structural contribution of Bruch's membrane and sclera to the ocular wall by comparing their biomechanical properties under tension.

The paper develops and validates a multiscale cortical circuit model to simulate TMS-evoked responses, revealing mechanisms of cortical activation and inhibition.

This paper develops a method to create 3D-printed collagen scaffolds with controlled fiber alignment patterns to guide cell orientation.

This paper develops AAV-STITCH, a method to target neuroblastoma cells using anti-GD2 ScFv coupled to AAV capsids, showing selective transduction and tumor suppression in mouse models.

This study develops a perfusion bioreactor system to co-culture hiPSC-derived erythromyeloid progenitors with neurospheres, mimicking microglial features in CNS development.

This study investigates how mice regulate body resonance and avoidance behavior during whole-body vibration across different axes, revealing axis-specific neuro-musculoskeletal control mechanisms.

This paper demonstrates biofuel-driven supramolecular nanowires with tunable conductance, showing n-type behavior and reversible conductance switching.

This paper develops a 3D human urothelial model to study UTI dynamics and therapeutic responses in real-time.

This paper introduces MindSight, a deep learning algorithm for cortical electrical stimulation to improve visual restoration, showing better performance in visual perception tasks with macaque monkeys.

This study develops anti-CD38 lipid nanoparticles for targeted mRNA delivery to multiple myeloma cells, improving tumor targeting and reducing hepatic accumulation.

The paper compares CRISPR/Cas9 gene editing efficiency in retinal organoids, HEK293T cells, and mouse models, finding retinal organoids better mirror in vivo editing outcomes.

This study develops a CD3-functionalized hydrogel to protect stem cell-derived beta cells from immune rejection in diabetes therapy.

This paper introduces SC-LSS, an automated tool for volumetric segmentation of Schlemms Canal in OCT images, showing high agreement with manual segmentation and detecting changes in SC size under different intraocular pressure conditions.