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The paper identifies spiking units in extracellular electrophysiological recordings of dispersed mycelial cultures, which are absent after dehydration or fungicidal treatment.

This paper presents a T cell gene correction pipeline using CRISPR/Cas9 and HDR to correct monogenic mutations in IEI models, achieving up to 80% bi-allelic editing with no detectable off-target effects.

This paper develops a personalized shoulder modeling framework that improves kinematic accuracy for multiple motions using closed-chain models with 5 DOFs.

This paper develops a machine learning-guided hydrogen-bonded organic framework for ultrasound-triggered pain therapy, showing effective long-term analgesia in a rat model.

This paper develops a bimodal imaging probe for monitoring systemic inflammation using immuno-PET and immuno-MRI, demonstrating its efficacy in a murine model of rhabdomyolysis.

This paper introduces a portable microfluidic device for highly multiplexed nucleic acid detection, demonstrating its integration with CRISPR-based technology for rapid pathogen and variant detection.

This paper develops a 3D printing method to create perfusable vascular constructs with tunable flow dynamics and permeability, validated through simulations and in vivo comparisons.

This paper introduces LGFN, a cross-modal dynamic fusion framework for music emotion recognition that improves accuracy by aligning lyrics and audio features through attentional alignment and dynamic gate fusion.

This study introduces a microfluidic platform called -Blood to monitor Babesia microti infection dynamics in whole blood without preprocessing, enabling extended observation of parasite-host interactions.

This paper introduces an oxygen-generating encapsulation system for insulin-secreting cells that supports high-density packing and reverses diabetes in rats without immunosuppression.

This study shows that in vivo maturation of MLP-KO iPSC-CMs recapitulates DCM phenotypes, while in vitro maturation does not.

This study shows that senescent bone cells' secretome causes spatially varied ECM changes and mechanical weakness in human brain organoids.

This paper compares the performance of three microbes in dissolving ultramafic rock dunite, finding that Gluconobacter oxydans outperforms the others in acid production and metal extraction.

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

This study investigates how PEGylated cationic PAMAM dendrimers interact with proteins in synovial fluid and how these interactions affect their uptake in cartilage and internalization by chondrocytes.

The paper uses simulation to show that multi-site tendon transfers can produce better-directed thumb-tip forces than single-site transfers for lateral pinch grasp in tetraplegia.

This paper introduces GTACs, bispecific antibodies that selectively downregulate GPCRs via endocytosis and lysosomal degradation, showing high potency and selectivity for therapeutic targets.

The paper presents a pipeline for 3D bioprinting microalgal constructs and simulating their photosynthetic performance using functional imaging and non-invasive techniques.

This paper develops a coronavirus-mimicking protein nanocage platform for targeted delivery of interferon to glioblastoma, showing improved BBB traversal and immune reprogramming.