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The paper investigates microdefects in hip-fracture patients and finds they are more prevalent and negatively correlate with bone strength.

This paper introduces PADAM, a time-domain passive cavitation imaging method that improves resolution and reduces artifacts compared to existing methods, enabling better cavitation monitoring and control in FUS therapy.

This paper introduces LO-VLM, a compact vision-language model for OCT analysis that improves accuracy and interpretability in retinal disease classification and summary generation.

This study develops SPM-dots as a multifunctional carrier for miRNA delivery and stem cell tracking, showing enhanced osteogenic differentiation and in vivo labeling.

This paper develops a nanovial-based platform to identify functional TCRs from unconventional T cells, isolating and validating five novel MAIT TCRs with antigen-specific activity.

This paper introduces 3D-RIM, a method that achieves super-resolved volume imaging of thick live specimens with high contrast and resolution across multiple microns.

This paper demonstrates a DNA origami structure with dynamic size-switchability using i-motif and hairpin motifs, enabling contraction and expansion between 68 nm and 150 nm.

This study evaluates a vitamin C-loaded hyaluronic acid/collagen scaffold for enhanced wound healing in rat models, showing improved fibroblast activity and reduced inflammation.

The paper introduces MSMCE, a module for raw mass spectrometry data classification that improves performance and efficiency by modeling inter-channel dependencies and using residual connections.

This paper develops an RNA base editor using CRISPR-Cas13 and ADAR2DD to correct mutations in inherited retinal diseases, showing up to 60% editing efficiency in vitro and partial rescue in mouse models.

This study uses pulsed speckle contrast optical spectroscopy to detect microclots in biofluids, showing decreased speckle contrast with increasing microclot concentration.

The paper shows that increasing proteasomal activity improves secreted protein production in ER-stressed cells, while autophagy inhibition also enhances secretion.

This paper designs and assembles a hollow two-lidded DNA box for drug delivery, demonstrating stability and cargo loading capabilities.

The paper evaluates how the functional avidity of anti-B7H3 CAR-T constructs relates to their ability to trigger effector function against tumors with varying antigen density.

This paper develops a Raman spectroscopy tool for real-time monitoring of attenuated CMV in flow, demonstrating its ability to detect viral particles at high flow rates and across concentrations.

The paper uses AI to generate a small MLH1 binder that enhances prime editing efficiency by disrupting MMR, resulting in the highest PE efficiency to date.

This paper develops a biologics-free 3D-printed nerve guidance conduit that restores motor function comparable to autografts in a mouse model.

This study shows that cyclic mechanical loading disrupts cytoskeletal symmetry in 3D scaffolds by combining matrix strain and fluid shear stress.

This paper introduces an automated framework for optimizing MRI RF coil design to improve SNR performance using full-wave electromagnetic simulations and ultimate SNR benchmarks.

This paper introduces a modular microfluidic system to create stiffness gradient hydrogels with complex profiles, showing their effectiveness in modulating cell behavior.