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This study shows that altered muscle niche in D2-mdx mice leads to poor myogenesis and increased degeneration, but reversing this improves regeneration in adult mice.

This study identifies detyrosinated microtubules as a driver of myofibrillar malformations in dystrophic skeletal muscle fibers, linking increased deTyr-MT levels to structural impairments.

This paper uses two transgenic mouse models to study APOL1 risk variants' effects on glomerular disease, identifying shared and distinct transcriptional changes in podocytes.

This study evaluates the effects of sodium nitrite reduction, removal, and replacement in ham on microbiological safety, colon health, and colorectal cancer risk in a rat model.

This study shows that a western diet impairs T regulatory cell function in NAFLD, leading to chronic inflammation and fibrosis, and suggests restoring Treg function as a potential therapy.

This study shows that deleting smooth muscle O-GlcNAc transferase (smOGT) reduces atherosclerosis in hyperglycemic ApoE-/- mice fed a Western diet.

This study uses a Drosophila model to distinguish between loss-of-function and dominant negative OPA1 mutations in DOA and DOA plus.

This study shows that hepatic IRE1 protects against septic cardiac failure by maintaining lipid metabolic balance, independent of inflammation.

This paper develops a thermosensitive hydrogel DDS for sustained delivery of anti-TNF and anti-VEGF drugs, showing long-term ocular protection after corneal injury.

This study investigates the role of platelet activating factor (PAF) signaling in hyperoxic neonatal lung injury and BPD by comparing WT and PAF receptor knockout mice.

This study shows ZIKV can transmit vertically through fetal membranes, not the placenta, in rhesus macaques.

This study shows repeated BTX injections in rat masticatory muscles cause consistent mandibular bone loss and enthesis hypertrophy without worsening with injection frequency.

The paper reports the first cases of H5N1 avian influenza in wild mammals in the US, showing neurological symptoms and lesions linked to bird-to-mammal spillover.

This study finds that myosin in DCM-affected dogs has increased super-relaxed state and is rescued by EMD-57033.

This study uses immunohistochemistry with a new antibody to show GPER expression varies across normal and cancer tissues.

The paper proposes a domain adaptation method for histopathology images that addresses class imbalance and improves transfer learning from labeled source to unlabeled target domains.

The paper models lineage displacement and coexistence in Phytophthora infestans using pathogenesis data to predict genotype fitness and composition changes across hosts.

The paper models COVID-19 as a continuous-time stochastic process to analyze extinction chances and outbreak patterns without considering immune individuals.

This study identifies a conserved microtubule-binding region in XopL that is essential for plant cell death, showing how effector localization relates to function across Xanthomonas species.

This study shows that c-di-GMP interacts with putrescine via the YcgR receptor to regulate bacterial motility in Dickeya oryzea, with c-di-GMP inhibiting putrescine's effect.