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This study analyzes HRV spectral features in Williams syndrome during sleep, finding altered fractal properties and associations with sleep structure indicators.

This study shows that primary cilia in cardiac fibroblasts promote fibrosis and impair heart function after myocardial infarction by amplifying fibrotic signaling.

This study examines how bile acid modulation affects colonic epithelial responses in mice and humans, finding altered cell populations and gene expression associated with DCA exposure.

This study shows REST is reduced in endometriosis and its deletion in mice causes progesterone resistance, subfertility, and larger endometriotic lesions.

This study shows that DSS-induced colitis suppresses hepatic SCD1 without affecting colitis severity, and reveals lipid metabolism changes in the liver and plasma.

This study shows that time-restricted feeding extends healthspan in both sexes and lifespan in male mice under normal dietary conditions.

This study compares cAMP and EPC-induced decidualization in 3D human endometrial organoids, finding that EPC induces broader and more physiologically relevant transcriptional changes.

This study uses fecal hormone metabolites to confirm spontaneous polyestry in captive Mount Graham red squirrels and highlights the importance of environmental conditions for reproductive success.

This study shows GLP-1R agonism directly improves lymphatic pumping capacity in mice through vasodilation and enhanced contractile function, independent of systemic weight loss effects.

This study shows that Robo4 deletion increases neuroinflammation and impairs motor coordination in Alzheimer's disease mice, with effects dependent on AD mutations and brain region.

This study investigates the effects of globin digest and its peptides on skeletal muscle hypertrophy and physical performance in zebrafish, mice, and myoblasts, finding significant improvements in muscle growth and motor function.

This study investigates the effects of non-ablative radiotherapy on cardiomyocyte electrophysiology and intracellular Ca2+ dynamics in mice, finding dose-dependent changes in ion currents, action potential parameters, and oxidative stress.

This study shows that genetic deletion of cytoglobin worsens cardiac hypertrophy and inhibits fibroblast activation in mice without affecting blood pressure.

A Cre-dependent ER-targeted TurboID knock-in mouse enables cell type-specific secretory proteomics, mapping adipocyte and hepatocyte responses to fasting, LPS and obesity, with B cells profiled at baseline.

This study validates fecal haptoglobin as a biomarker of inflammation in wild capuchin monkeys and finds environmental factors, not demographic or circadian variables, influence its concentrations.

This study shows that cricket nymphs clear microplastics through frass production before moulting, and that moulting timing is not affected by continuous microplastic ingestion.

This study identifies and classifies three types of mechanosensitive bladder afferents based on their responses to physiological and noxious distension.

This study shows that S-nitrosylation of PKA regulatory subunits by SCAN is required for GPCR-induced PKA activation in heart, brain, and fat tissues.

This study uses FRET-based imaging to measure real-time cGMP levels in arterioles of live mice, showing PDEs affect signaling duration but not amplitude, and ACh does not induce endothelial NO release.