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Nine vastus lateralis biopsies from before exercise to 48 h after one high-intensity interval session reveal 16,625 exercise-responsive genes; only four respond differently between males and females.

This study compares morpho-biometric traits of two Mozambican goat breeds, identifying phenotypic differences that support breed characterization and conservation strategies.

This study shows corticosteroids increase intraocular pressure by suppressing TREK-1 channels in trabecular meshwork cells, leading to ocular hypertension, which can be counteracted by TREK-1 agonists.

This study shows TMAO affects cell type-specific pathways in mouse aorta, promoting atherosclerotic plaque instability by increasing apoptosis and reducing ECM formation.

This paper constructs the first comorbidity networks in companion dogs using data from the Dog Aging Project, revealing both well-known and novel disease associations and their temporal relationships.

This study examines the effects of three months of high-intensity interval training on physical and cognitive function in middle-aged male mice, finding improved aerobic capacity but no significant cognitive benefits.

The paper examines metabolic changes during pregnancy in marmosets and mice to identify models for studying morning sickness, finding transient weight loss in marmosets and altered food intake in mice.

This study identifies wheat genotypes with higher transpiration efficiency by developing a high-throughput phenotyping framework and shows their potential for drought-resilient breeding.

This paper introduces a second-order Poincare plot to analyze heart rate variability, revealing respiratory effects through serial dependencies in RR intervals.

This paper develops shear-activated nanoparticles delivering nitroglycerin to improve ischaemic stroke outcomes by enhancing collateral vessel perfusion.

The paper introduces KneEZ Clear, an aqueous-based tissue clearing method for musculoskeletal tissues that preserves fluorescence and avoids equipment requirements.

This study shows that meal timing affects gut circadian rhythms, with interval feeding disrupting IEC clock transcripts and microbiota rhythms.

The paper investigates neural correlates of perceptual grouping using EEG, finding early cortical differences in responses to structured versus unstructured visual stimuli.

This study examines the effects of dietary CBD on circadian rhythms, sleep, lifespan, close-proximity rhythm, egg reproduction, and motor function in Drosophila melanogaster.

This study shows that ablating three key phospho-sites in RyR2 preserves adrenergic responses but increases arrhythmogenic risk by altering Ca2+ leak and promoting early afterdepolarizations.

This study shows that exendin-4 improves bone strength in ovariectomized mice through a central mechanism, not directly on bone cells.

This study identifies a vagal sensory-hypothalamic oxytocin-brown adipose tissue pathway that mediates CCK-induced thermogenesis.

This study identifies changes in the skeletal muscle nuclear proteome after acute exercise, revealing post-transcriptional effects on mRNA processing and splicing.

This study examines the transcriptomic and metabolomic responses of Lucinoma capensis to hypoxia and reoxygenation, revealing organ-specific adaptations and symbiotic mechanisms that support survival in oxygen minimum zones.

This paper develops sex-specific human electromechanical models to simulate and evaluate sex differences in drug responses and ECG biomarkers, revealing ionic and anatomical mechanisms underlying these differences.