Author

Bigang Liu

The University of Texas MD Anderson Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

John R. HortoniD· 2 shared Jujun ZhouiD· 2 shared Taiping CheniD· 2 shared Xiaodong ChengiD· 2 shared Abhinav K. JainiD· 1 shared Antonello MaiiD· 1 shared Bin LiuiD· 1 shared Caleb ChangiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersMolecular Biology

John R. HortonORCID

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2 papers

Recent·Most cited

Quinoline-based compounds can inhibit diverse enzymes that act on DNA

Jujun Zhou, Qin Chen, Ren Ren, Jie Yang, Bigang Liu, John R. Horton, Caleb Chang, Chuxuan Li, Leora Maksoud, Yifei Yang, Dante Rotili, Abhinav K. Jain, Xing Zhang, Robert Blumenthal, Taiping Chen, , Xiaodong Cheng

This study identifies quinoline-based compounds that inhibit DNA methyltransferases and other DNA-targeting enzymes, with compound 11 inducing DNA damage response in cancer cells.

Cell chemical biology · Oct 21, 2024Peer-reviewedMolecular Biology

The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA

Swanand Hardikar, Ren Ren, Zhengzhou Ying, Jujun Zhou, John R. Horton, Matthew D. Bramble, Bin Liu, Yue Lu, Bigang Liu, Luis Della Coletta, Jianjun Shen, Jiameng Dan, Xing Zhang, Xiaodong Cheng, Taiping Chen

The paper identifies a unique DNA-binding domain in CDCA7 that recognizes a CpG dyad in non-B DNA, linking it to DNA methylation specificity in ICF syndrome.

Science Advances · Aug 23, 2024Peer-reviewedMolecular Biology