Author

S. A. Summers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Physiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

W. L. Holland· 3 shared A. M. Nuotio-Antar· 1 shared A. R. Cox· 1 shared A. Vivoli· 1 shared A.-L. Castell· 1 shared B. A. Kiapparettu· 1 shared B. Chaurasia· 1 shared B. J. Brintz· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

W. L. Holland

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Integrating molecular and clinical variables to predict myocardial recovery

J. R. Visker, B. J. Brintz, C. P. Kyriakopoulos, Y. Hillas, I. Taleb, R. Badolia, T. S. Shankar, J. M. Amrute, J. Ling, R. Hamouche, E. Tseliou, S. Navankasattusas, O. Wever-Pinzon, G. S. Ducker, W. L. Holland, , S. G. Drakos

This study integrates clinical and transcriptomic data to predict myocardial recovery in heart failure patients after LVAD implantation, identifying 80 features with an AUC of 0.731.

bioRxiv · Apr 16, 2024 · PreprintPhysiology

Vitamin B2 enables peroxisome proliferator-activated receptor α regulation of fasting glucose availability

P. M. Masschelin, P. Saha, S. A. Ochsner, A. R. Cox, K. H. Kim, J. B. Felix, R. Sharp, X. Li, L. Tan, J. H. Park, L. Wang, V. Putluri, P. L. Lorenzi, A. M. Nuotio-Antar, Z. Sun, , S. M. Hartig

This study shows that vitamin B2 deficiency impairs PPAR regulation of fasting glucose, and PPAR agonists can rescue this defect.

bioRxiv · Oct 16, 2022Physiology

Very Long-Chain Unsaturated Sphingolipids Mediate Oleate-Induced Rat β-Cell Proliferation

A.-L. Castell, A. Vivoli, T. S. Tippetts, I. Robillard Frayne, V. S. Moulle, M. Ruiz, J. Ghislain, C. Des Rosiers, W. L. Holland, S. A. Summers, V. Poitout

This study shows that oleate induces β-cell proliferation in rats via unsaturated very long-chain sphingolipids, mediated by ACBP and ELOVL1.

bioRxiv · Jul 16, 2021Cell Biology

Serine Palmitoyltransferase Controls Stemness of Intestinal Progenitors

S. A. Summers, B. Chaurasia, Y. Li, V. Kaddai, J. L. Wilkerson, J. A. Maschek, J. Cox, P. Wei, C. Bensard, P. J. Meikle, H. Clevers, J. Shayman, Y. Hirabayashi, W. L. Holland, J. Rutter

The paper shows that serine palmitoyltransferase (SPT) modulates intestinal stem cell homeostasis by promoting stemness through sphingolipid production and PPAR-alpha activation, linking diet to cancer risk.

bioRxiv · Dec 3, 2020 · PreprintCell Biology