Author

Cindy Manriquez-Rodriguez

La Jolla Institute for Immunology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Samuel A. MyersiD· 3 shared Amanda T. Jeng· 1 shared Anjana RaoiD· 1 shared Anthony J. KoleskeiD· 1 shared Aurélie Modat· 1 shared Caitlin Brown· 1 shared Charles A. GreeriD· 1 shared Denise Dunn· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

Samuel A. MyersORCID

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Author profile →

3 papers

Recent·Most cited

Evidence for Functional Regulation of the KLHL3/WNK Pathway by O-GlcNAcylation

Jimin Hu, Duc T. Huynh, Denise Dunn, Jianli Wu, Cindy Manriquez-Rodriguez, Qianyi E Zhang, Gabrielle A. Hirschkorn, Tetsuya Hirata, George R Georgiou, Samuel A. Myers, Scott Floyd, Jen‐Tsan Chi, Michael Boyce

This study shows that KLHL3 and WNK kinases are regulated by O-GlcNAcylation, affecting osmolarity control and ferroptosis, with implications for blood pressure and neuronal health.

Glycobiology · Aug 11, 2025Peer-reviewedCell Biology

Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice.

Yevheniia Ishchenko, Amanda T. Jeng, Shufang Feng, Timothy Nottoli, Cindy Manriquez-Rodriguez, Khanh K Nguyen, Melissa G Carrizales, Matthew J Vitarelli, Ellen E Corcoran, Charles A. Greer, Samuel A. Myers, Anthony J. Koleske

This study examines how different heterozygous TRIO variants in mice affect behavior, brain development, and synaptic function, revealing distinct phenotypes linked to neurodevelopmental disorders.

eLife · Jun 9, 2025Peer-reviewedNeuroscience

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepúlveda, Xiang Li, Leo J. Arteaga-Vazquez, Isaac F. López-Moyado, Melina Brunelli, Lot Hernández-Espinosa, Xiaojing Yue, J. Carlos Angel, Caitlin Brown, Zhen Dong, Natasha Jansz, Fabio Puddu, Aurélie Modat, Jamie Scotcher, Páidí Creed, , Anjana Rao

This study shows that OGT inhibits TET activity, preventing DNA demethylation and transposable element expression in heterochromatin.

Nature Structural & Molecular Biology · Mar 28, 2025Peer-reviewedMolecular Biology