The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion
Grigorios Panteloglou, Jérôme Robert, Marieke Smit, Nicolette Huijkman, Niels Kloosterhuis, Christopher S. Law, Brian Woods, Alaa Othman, Marcus Edi Kleber, Graciela Delgado, Patrizia Tarugi, Museer A. Lone, Justina Clarinda Wolters, Antoine Rimbert, Anja Kerksiek, , Arnold von Eckardstein
This study identifies COPI coatomer subunits that regulate LDL receptor activity, apoB secretion, and hepatic lipid storage, with genetic variants linked to elevated LDL-C levels.
Atherosclerosis · Aug 25, 2026Peer-reviewedCell Biology