Author

H. Zhai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 3 Bioengineering· 1 Biophysics· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:development & morphogenesis· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:imaging· 2

Frequent Co-Authors

C. Li· 2 shared F. Wu· 2 shared H. Chen· 2 shared L. Qi· 2 shared A. A. Sinha· 1 shared A. C. Borgeaud· 1 shared A. Ostadi Moghaddam· 1 shared B. Tajvidi Safa· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersPlant Biology

C. Li

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Desmosomal Cadherin Tension Loss in Pemphigus Vulgaris Mediated by the Inhibition of Active RhoA at Cell-Cell Adhesions

X. Jin, J. Rosenbohm, A. Ostadi Moghaddam, E. Kim, K. Seiffert-Sinha, M. Leiker, H. Zhai, S. R. Baddam, G. Minnick, Y. Huo, B. Tajvidi Safa, J. K. Wahl, F. Meng, C. Huang, J. Y. Lim, , R. Yang

This study shows that PV antibodies cause tension loss at desmosomes and cell-cell adhesions by inhibiting RhoA, which can be partially reversed by altering actomyosin contractility.

bioRxiv · May 3, 2024Biophysics

Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells

Y. Huang, H. Mo, J. Yang, L. Gao, T. Tao, Q. Shu, W. Guo, Y. Zhao, J. Lyu, Q. Wang, J. Guo, H. Zhai, L. Zhu, H. Chen, G. Xu

This study shows that Piezo1 in intestinal L cells mechanically regulates GLP-1 production, affecting glucose tolerance and diabetes.

bioRxiv · Apr 1, 2024Physiology

Guanylate cyclase activity of TIR1/AFB auxin receptors mediates rapid auxin responses

L. Qi, H. Zhai, H. Chen, M. Kwiatkowski, J. Liao, M. Lu, Y. Pei, Y. Gao, P. Yun, L. Li, S. Shabala, E. Farmer, K. Jaworski, J. Friml

The paper shows TIR1/AFB auxin receptors have both adenylate and guanylate cyclase activities, mediating transcriptional reprogramming and rapid Ca2+-dependent growth responses.

bioRxiv · Nov 18, 2023 · PreprintPlant Biology

Tomato CYP94C1 terminates jasmonate signaling during fruit ripening by inactivating bioactive jasmonoyl-L-isoleucine

T. Yang, L. Deng, C. Sun, M. Ali, F. Wu, H. Zhai, Q. Xu, P. Xin, J. Chu, T. Huang, C.-B. Li, C. Li

This study identifies CYP94C1 as a key enzyme in tomato that terminates jasmonate signaling during ripening by converting bioactive JA-Ile to an inactive form, thereby reducing susceptibility to necrotrophic pathogens.

bioRxiv · May 17, 2023 · PreprintPlant Biology

Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization

Y. Liu, H. Zhai, H. Alemayehu, J. Boulanger, L. J. Hopkins, A. C. Borgeaud, C. Heroven, J. D. Howe, K. E. Leigh, C. E. Bryant, Y. Modis

The paper uses cryo-electron tomography to reveal the ultrastructure of ASC specks and gasdermin D pores in NLRP3-activated cells.

bioRxiv · Sep 20, 2021Immunology

Experimental study of tissue-engineered urethra with collagen / chitosan composite as scaffolds

H. Zhai, C. Qiu, J. Jin, X. Shao

The paper investigates tissue-engineered urethra using collagen/chitosan scaffolds and reports a new method for quantifying epithelial cell activity.

bioRxiv · Apr 30, 2020 · PreprintBioengineering

Elongator is required for root stem cell maintenance by regulating SHORT ROOT transcription

Q. Chen, C. Li, L. Qi, X. Zhang, H. Zhai, J. Liu, F. Wu

This study shows that Elongator regulates SHORT ROOT transcription in Arabidopsis roots, essential for stem cell maintenance and radial patterning.

bioRxiv · Jan 22, 2018Plant Biology