Author

J. E. Hinshaw

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Assay:cryo-EM· 3 Approach:microscopy & imaging analysis· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1 Assay:electronic health records· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

J. R. Jimah· 3 shared N. Kundu· 2 shared A. D. Roberts· 1 shared A. Frost· 1 shared A. Somasundaram· 1 shared B. Carragher· 1 shared B. L. Heine· 1 shared B. Malone· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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3 shared papersCell Biology

J. R. Jimah

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding

M. T. Doyle, J. R. Jimah, J. E. Hinshaw, H. D. Bernstein

The paper uses cryo-EM to study bacterial outer membrane protein folding, revealing hybrid-barrel intermediates and how BAM uses membrane elasticity to facilitate folding.

Cell · Mar 1, 2022Peer-reviewedBiochemistry

Molecular mechanics underlying flat-to-round membrane budding in live secretory cells

W. Shin, B. Zucker, N. Kundu, S. H. Lee, B. Shi, X. Guo, C. Y. Chan, J. T. Harrison, J. M. Turechek, J. E. Hinshaw, M. Kozlov, L.-G. Wu

The paper identifies actin filaments and dynamin as key forces mediating non-coated membrane budding in live cells, revealing mechanisms that transform flat membranes into vesicles.

bioRxiv · Feb 2, 2022Cell Biology

Time-resolved cryoEM using Spotiton

V. P. Dandey, W. C. Budell, H. Wei, D. Bobe, K. Maruthi, M. Kopylov, E. T. Eng, P. A. Kahn, J. E. Hinshaw, N. Kundu, C. M. Nimigean, C. Fan, N. Sukomon, S. Darst, R. Saecker, , B. Carragher

The paper introduces a method for preparing cryoEM grids to study short-lived molecular states by rapidly dispensing sample drops and vitrifying them.

Microscopy and Microanalysis · Jul 30, 2020Peer-reviewedBiophysics

The structure and spontaneous curvature of clathrin lattices at the plasma membrane.

K. A. Sochacki, B. L. Heine, G. J. Haber, J. R. Jimah, B. Prasai, M. A. Alfonzo-Mendez, A. D. Roberts, A. Somasundaram, J. E. Hinshaw, J. W. Taraska

This study determines the structural framework of clathrin-mediated endocytosis, showing flat clathrin lattices spontaneously curve into coated pits without external factors.

bioRxiv · Jul 18, 2020Cell Biology

The mechanisms of dynamin-actin interaction

R. Zhang, N. Gerassimov, D. M. Lee, J. R. Jimah, S. Kim, D. Luvsanjav, J. Winkelman, M. Mettlen, M. E. Abrams, R. Kalia, P. Keene, P. Pandey, B. Ravaux, J. H. Kim, J. A. Ditlev, , E. H. Chen

This study identifies a noncanonical role for dynamin in cell-cell fusion by directly bundling actin filaments through GTPase-dependent interactions.

bioRxiv · Mar 25, 2019 · PreprintCell Biology