J. Sun

This study identifies a common pattern of viral gene expression heterogeneity in influenza A virus that influences host antiviral responses across subtypes.

This study identifies proinsulin self-association as a mechanism driving dominant-negative effects of misfolded proinsulin in MIDY, offering a therapeutic target for enhancing insulin production.

This study evaluates two tDCS optimization schemes for single and multi-target brain stimulation, showing that parameter settings significantly affect outcomes, especially in multi-target cases, and proposes improved weighted schemes.

CASLFA enables rapid, specific detection of pathogens and GMOs with high sensitivity and no technical expertise.

The paper isolates and characterizes seven phages infecting Roseobacter RCA lineage bacteria, revealing genomic diversity and abundance in marine virosphere.

This study uses CFD simulations to analyze how oral appliances alter upper airway morphology and airflow dynamics in OSAHS patients, showing reduced resistance and improved patency.

This study identifies ALI-1 as a candidate gene for the B1 locus, showing its role in regulating awn length and grain weight in wheat through cytokinin suppression.

This paper develops a CRISPR-based colorimetric gene detection platform using AuNPs that enables naked-eye detection of DNA and RNA targets with high sensitivity and universality.

This paper develops a deep learning scheme to classify M. marinum-infected and uninfected macrophages based on morphology, achieving high accuracy at early infection stages.

This study identifies key gut bacteria correlated with systemic iron levels using a murine model and bioinformatic tools, establishing a non-invasive prediction model for iron-related diseases.

This study shows that inhibiting SCD1 reduces TFH cell activity and germinal center B cell responses, linking fatty acid metabolism to immune responses.

This paper elucidates the compartmentalized biosynthetic pathway of mycophenolic acid, revealing subcellular localization of enzymes and cooperation with β-oxidation machinery.

This paper identifies and characterizes a novel paraoxonase-like enzyme in Trichoderma atroviride strain T23 that degrades DDVP and related organophosphate-oxons, showing high activity and specific kinetic parameters.

This study identifies 11 new pelagiphages in the Podoviridae family that integrate into host SAR11 genomes, providing evidence of both lytic and lysogenic infection mechanisms.

This study measures TEP concentrations, sinking rates, and export flux in the Changjiang estuary, showing TEPs act as a significant carbon sink in eutrophic coastal waters.

This study identifies and characterizes WRKY genes in melon, analyzes their evolution, and assesses their role in powdery mildew resistance.

This study identifies that the number of viral genes expressed, not their identity, determines influenza A virus superinfection susceptibility.

The paper analyzes splicing evolution across human, chimpanzee, and macaque lineages, finding that changes in exon inclusion frequency are more functionally relevant than constitutive-to-alternative transitions.

This paper demonstrates that Rhodosporidium toruloides can efficiently convert lignocellulosic hydrolysates into terpenes like bisabolene and amorphadiene, outperforming purified substrates in productivity.

This study applies Mondrian cross-conformal prediction to estimate prediction confidence on large imbalanced bioactivity datasets, showing improved performance for minority classes.