Author

J. V. Nayak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 5 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. T. Bravo· 3 shared A. A. Salahudeen· 2 shared C. J. Kuo· 2 shared C. M. Lee· 2 shared G. Bao· 2 shared J. J. Wine· 2 shared M. T. Chang· 2 shared S. Vaidyanathan· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

D. T. Bravo

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Immune-Epithelial Dynamics and Tissue Remodeling in Chronically Inflamed Nasal Epithelium via Multi-scaled Transcriptomics

G. Liao, T. Nakayama, I. T. Lee, B. Zhu, J. B. Overdevest, C. H. Yan, D. Zarabanda, P. A. Gall, S. S. Dholakia, N. A. Borchard, A. Yang, D. Kim, D. T. Bravo, Z. M. Patel, P. H. Hwang, , S. Jiang

This study uses multi-scaled transcriptomics to investigate immune-epithelial dynamics and tissue remodeling in chronic rhinosinusitis, identifying novel cellular interactions and trajectories associated with nasal polyps.

bioRxiv · Jul 1, 2023 · PreprintImmunology

Development of a shortwave infrared (SWIR) sinuscope for the detection of cerebrospinal fluid (CSF) leaks

T. W. Klein, S. Yang, M. A. Tusty, J. V. Nayak, M. T. Chang, O. T. Bruns, T. S. Bischof, T. A. Valdez

This paper develops a shortwave infrared sinuscope to detect cerebrospinal fluid leaks without contrast agents, showing that CSF has an absorption profile similar to water.

bioRxiv · Dec 22, 2022 · PreprintBioengineering

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus

S. Vaidyanathan, R. Baik, L. Chen, D. T. Bravo, C. J. Suarez, S. M. Abazari, A. A. Salahudeen, A. M. Dudek, C. A. Teran, T. H. Davis, C. M. Lee, G. Bao, S. H. Randell, S. E. Artandi, J. J. Wine, , M. Porteus

This study corrects multiple CFTR mutations in human airway stem cells using CRISPR/Cas9 and AAV vectors, achieving functional restoration in differentiated epithelial cells.

bioRxiv · Feb 26, 2021Bioengineering

Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models

X. Li, P. Lidsky, Y. Xiao, C.-T. Wu, M. Garcia-Knight, J. Yang, T. Nakayama, J. V. Nayak, P. K. Jackson, R. Andino, X. Shu

This study identifies ethacridine, an FDA-approved antiseptic, as a potent inhibitor of SARS-CoV-2 by inactivating viral particles in cellular models.

bioRxiv · Oct 28, 2020Microbiology

Highly Efficient Repair of the ΔF508 Mutation in Airway Stem Cells of Cystic Fibrosis Patients with Functional Rescue of the Differentiated Epithelia

S. Vaidyanathan, A. A. Salahudeen, Z. M. Sellers, D. T. Bravo, S. S. Choi, A. Batish, W. Le, S. De La O, M. P. Kaushik, N. Galper, C. M. Lee, G. Bao, E. H. Chang, J. J. Wine, C. E. Milla, , M. H. Porteus

This paper corrects the ΔF508 mutation in CF patient airway stem cells using CRISPR-Cas9 and AAV6, achieving high correction rates and functional rescue in differentiated epithelia.

bioRxiv · Feb 26, 2019 · PreprintBioengineering