Author

K. Aihara

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

S. Iwami· 5 shared K. Watashi· 4 shared H. Park· 3 shared K. S. Kim· 3 shared N. Nakamura· 3 shared A. S. Perelson· 2 shared K. Ejima· 2 shared K. Kim· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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5 shared papersMicrobiology

S. Iwami

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Stratification of viral shedding patterns in saliva of COVID-19 patients

H. Park, Y. Raiki, S. Iwanami, K. Kim, K. Ejima, N. Nakamura, K. Aihara, Y. Miyazaki, T. Umeyama, K. Miyazawa, T. Morita, K. Watashi, C. B. Brooke, R. Ke, S. Iwami, T. Miyazaki

This study stratifies SARS-CoV-2 viral shedding patterns in saliva into three groups with distinct durations using a mathematical model and clustering, but finds no clear clinical or miRNA biomarkers explaining the differences.

bioRxiv · Jan 30, 2024Microbiology

Multiscale modeling of HBV infection integrating intra- and intercellular viral propagation for analyzing extracellular viral markers

K. Kitagawa, K. Kim, M. Iwamoto, S. Hayashi, H. Park, T. Nishiyama, N. Nakamura, Y. Fujita, S. Nakaoka, K. Aihara, A. S. Perelson, L. Allweiss, M. Dandri, K. Watashi, Y. Tanaka, S. Iwami

This study develops a multiscale mathematical model to predict intrahepatic cccDNA dynamics using serum viral markers, offering a non-invasive method for HBV infection analysis.

bioRxiv · Jun 6, 2023 · PreprintMicrobiology

Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolution

J. Sunagawa, K. S. Kim, H. Park, R. Komorizono, S. Choi, L. R. Torres, J. Woo, Y. D. Jeong, W. S. Hart, R. N. Thompson, K. Aihara, S. Iwami, R. Yamaguchi

This study shows isolation measures during the pandemic selected for SARS-CoV-2 variants with earlier and higher peak viral loads but shorter infection duration.

bioRxiv · Feb 23, 2023Evolutionary Biology

Prediction of elimination of intrahepatic cccDNA in hepatitis B virus-infected patients by a combination of noninvasive viral markers

S. Iwami, M. Iwamoto, T. Wakita, K. Watashi, A. S. Perelson, Y. Tanaka, M. Dandri, K. Aihara, M. Muramatsu, S. Iwami, E. Kawakami, L. Allweiss, P. Tangkijvanich, N. Chuaypen, M. Atsukawa, , Y. Fujita

This study develops a noninvasive method using viral markers to predict cccDNA levels in HBV patients, validated against liver biopsy data.

bioRxiv · Nov 4, 2022 · PreprintMicrobiology

Multidrug treatment with nelfinavir and cepharanthine against COVID-19

H. Ohashi, K. Watashi, W. Saso, K. Shionoya, S. Iwanami, T. Hirokawa, T. Shirai, S. Kanaya, Y. Ito, K. S. Kim, K. Nishioka, S. Ando, K. Ejima, Y. Koizumi, T. Tanaka, , T. Wakita

This study identifies a new multidrug combination treatment for COVID-19 using nelfinavir and cepharanthine, showing synergistic antiviral effects and improved disease control.

bioRxiv · Apr 14, 2020 · PreprintMicrobiology