Author

L. F. Dagley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. I. Webb· 3 shared A. Bankovacki· 1 shared A. C. Ching· 1 shared A. D. Uboldi· 1 shared A. M. Lehane· 1 shared A. Preaudet· 1 shared A. W. Burgess· 1 shared B. Lee· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersImmunology

A. I. Webb

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Caspase-2 protects against ferroptotic cell death

S. Dawar, M. C. Benitez, Y. Lim, T. A. Dite, J. M. Yousef, N. Thio, S. Garciaz, T. D. Jackson, J. V. Milne, L. F. Dagley, W. A. Phillips, S. Kumar, N. J. Clemons

This study shows caspase-2 protects mutant-p53 cancer cells from ferroptotic death by non-proteolytically interacting with proteins to limit GPX4 degradation.

bioRxiv · Aug 22, 2023Cancer Biology

TGF-beta1 induced S100 family protein expression is associated with epithelial to mesenchymal transition states and poor survival in pancreatic cancer

R. R. J. Low, K. Y. Fung, H. Gao, A. Preaudet, L. F. Dagley, J. Yousef, B. Lee, R. H. Larsen, N. J. Kershaw, A. W. Burgess, P. Gibbs, F. Hollande, M. D. W. Griffin, S. M. Grimmond, T. L. Putoczki

The paper links TGF-beta1-induced S100 family protein expression to EMT states and poor survival in pancreatic cancer using a murine organoid biobank.

bioRxiv · Feb 25, 2022 · PreprintCancer Biology

Physiological Substrates and Ontogeny-Specific Expression of the Ubiquitin Ligases MARCH1 and MARCH8

P. Schriek, H. Liu, A. C. Ching, P. Huang, N. Gupta, K. R. Wilson, M. Tsai, Y. Yan, C. F. Macri, L. F. Dagley, G. Infusini, A. I. Webb, H. McWilliam, S. Ishido, J. D. Mintern, J. A. Villadangos

This study identifies MARCH1 and MARCH8 as specialized regulators of CD4+ T cell immunity in distinct cellular compartments by analyzing their substrates and expression in mice.

bioRxiv · Apr 15, 2021Immunology

A regulatory interface on RIPK2 is required for XIAP binding and NOD signaling activity

V. J. Heim, L. F. Dagley, C. Stafford, F. M. Hansen, E. Clayer, A. Bankovacki, A. I. Webb, I. S. Lucet, J. Silke, U. Nachbur

The paper identifies a regulatory interface on RIPK2 essential for XIAP binding and NOD signaling by analyzing post-translational modifications in RIPK2 knock-in mice.

bioRxiv · Mar 12, 2020Cell Biology

Protein Kinase A Negatively Regulates Ca2+ signalling in Toxoplasma gondii

A. D. Uboldi, M.-L. Wilde, E. A. McRae, R. J. Stewart, L. F. Dagley, L. Yang, N. J. Katris, S. V. Hapuarachchi, M. J. Coffey, A. M. Lehane, C. Y. Botte, R. F. Waller, A. I. Webb, C. J. Tonkin

This study shows that Protein Kinase A (PKAc1) suppresses Ca2+ signalling in Toxoplasma gondii after host cell invasion, affecting motility and infectivity.

bioRxiv · Feb 14, 2018Microbiology