Author

R. F. Waller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 8 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell signaling & trafficking· 6 Research Focus:cell type annotation· 5 Research Focus:development & morphogenesis· 3 Research Focus:host-pathogen & immune response· 3 Approach:microscopy & imaging analysis· 3 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

E. C. Tromer· 4 shared K. Barylyuk· 4 shared L. Koreny· 4 shared D. Brady· 3 shared H. Ke· 3 shared M. Zeeshan· 3 shared N. J. Katris· 3 shared R. Tewari· 3 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersCell Biology

E. C. Tromer

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Apical annuli are specialised sites of post-invasion secretion of dense granules in Toxoplasma

S. Chelaghma, H. Ke, K. Barylyuk, T. Krueger, L. Koreny, R. F. Waller

This study identifies apical annuli in Toxoplasma gondii as specialized sites for post-invasion secretion of dense granules, essential for parasite growth and host cell remodeling.

bioRxiv · Jul 26, 2023Cell Biology

Stable and ancient endocytic structures navigate the complex pellicle of apicomplexan parasites

L. Koreny, B. N. Mercado-Saavedra, C. M. Klinger, K. Barylyuk, S. Butterworth, J. Hirst, Y. Rivera-Cuevas, N. R. Zaccai, V. J. C. Holzer, A. Klingl, J. B. Dacks, V. B. Carruthers, M. S. Robinson, S. Gras, R. F. Waller

This study identifies stable endocytic structures in Toxoplasma, showing their conservation across Apicomplexa and their role in plasma membrane homeostasis rather than nutrition.

bioRxiv · Jun 2, 2022 · PreprintCell Biology

Repurposing of Synaptonemal Complex Proteins for Kinetochores in Kinetoplastida

E. C. Tromer, T. A. Wemyss, R. F. Waller, B. Akiyoshi

The paper identifies homology between kinetoplastid kinetochore proteins and synaptonemal complex components, suggesting kinetoplastids repurposed meiotic machinery for their unique kinetochore system.

bioRxiv · Feb 6, 2021Cell Biology

Conservation of the Toxoplasma conoid complex proteome reveals a cryptic conoid in Plasmodium that differentiates between blood- and vector-stage zoites

L. Koreny, M. Zeeshan, K. Barylyuk, E. C. Tromer, J. J. E. van Hooff, D. Brady, H. Ke, S. Chelaghma, D. J. P. Ferguson, L. Eme, R. Tewari, R. F. Waller

The paper uses spatial proteomics and microscopy to show the conoid is conserved across apicomplexans, including Plasmodium, with structural differences between blood and vector stages.

bioRxiv · Jun 26, 2020Cell Biology

Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation

M. Zeeshan, R. Pandey, D. J. P. Ferguson, E. C. Tromer, R. Markus, S. Abel, D. Brady, E. Daniel, R. R. Stanway, A. R. Bottrill, K. G. Le Roch, A. A. Holder, R. F. Waller, D. S. Guttery, R. Tewari

The paper studies the dynamics of the NDC80 complex in Plasmodium berghei to reveal unique chromosome segregation mechanisms during parasite proliferation.

bioRxiv · May 12, 2020Cell Biology

A subcellular atlas of Toxoplasma reveals the functional context of the proteome

K. Barylyuk, L. Koreny, H. Ke, S. Butterworth, O. M. Crook, I. Lassadi, V. Gupta, E. C. Tromer, T. Mourier, T. J. Stevens, L. M. Breckels, A. Pain, K. S. Lilley, R. F. Waller

This study maps the subcellular locations of thousands of proteins in Toxoplasma gondii to reveal their functional contexts and evolutionary adaptations.

bioRxiv · Apr 23, 2020 · PreprintCell Biology

Systematic analysis of Plasmodium myosins reveals differential expression, localization and function in invasive and proliferative parasite stages

R. J. Wall, M. ZEESHAN, N. J. Katris, R. Limenitakis, E. Rea, J. Stock, D. Brady, R. F. Waller, A. A. Holder, R. Tewari

This study systematically analyzes Plasmodium myosins, revealing their differential expression, localization, and functional roles in invasive and proliferative parasite stages.

bioRxiv · Jun 14, 2019Cell Biology

Calcium negatively regulates secretion from dense granules in Toxoplasma gondii.

N. J. Katris, G. I. McFadden, G. G. van Dooren, R. F. Waller

This study shows that calcium negatively regulates dense granule exocytosis in Toxoplasma gondii, dependent on calcium-dependent protein kinases TgCDPK1 and TgCDPK3.

bioRxiv · Aug 7, 2018Cell Biology

Strength in numbers: collaborative science for new experimental model systems

R. F. Waller, P. A. Cleves, M. Rubio-Brotons, A. Woods, S. J. Bender, V. Edgcomb, E. R. Gann, A. C. Jones, L. Teytelman, P. von Dassow, S. W. Wilhelm, J. L. Collier

The paper describes a collaborative initiative to develop genetic models for marine protists, highlighting the approach, achievements, and lessons learned.

bioRxiv · Apr 26, 2018Microbiology

Protein Kinase A Negatively Regulates Ca2+ signalling in Toxoplasma gondii

A. D. Uboldi, M.-L. Wilde, E. A. McRae, R. J. Stewart, L. F. Dagley, L. Yang, N. J. Katris, S. V. Hapuarachchi, M. J. Coffey, A. M. Lehane, C. Y. Botte, R. F. Waller, A. I. Webb, C. J. Tonkin

This study shows that Protein Kinase A (PKAc1) suppresses Ca2+ signalling in Toxoplasma gondii after host cell invasion, affecting motility and infectivity.

bioRxiv · Feb 14, 2018Microbiology