L. Xiao

This study compares the DNBSEQ-G400 and Illumina MiSeq platforms for metabarcoding fungal communities, finding DNBSEQ-G400 to be more accurate, less biased, and cost-effective.

The study tracks vagino-cervical microbiome changes in 60 women over a year after oral probiotics, finding no colonization but stability in Lactobacillus-dominated communities and potential benefits for some individuals.

This paper introduces ScatNet, a deep-learning method for restoring 3D fluorescence microscopy images of turbid biological specimens, improving resolution and signal-to-noise ratio.

This study identifies circ_0005962 as an oncogene in NSCLC that promotes progression via the circ_0005962/miR-382-5p/PDK4 regulatory network.

This study identifies a non-hypermucoviscous ST11 hypervirulent K. pneumoniae strain lacking classical virulence factors, showing increased virulence through ampR and WcaJ mechanisms.

This study isolates and characterizes a coronavirus from Malayan pangolins that is highly similar to 2019-nCoV, suggesting pangolins may act as an intermediate host.

The paper compares fecal microbial compositions between female osteoporotic patients and healthy controls, identifying bacterial taxa associated with osteoporosis and demonstrating predictive power using a random forest model.

The paper presents a large multi-omic cohort of 2,183 adults to identify correlations between gut microbiome features and various health-related factors, validated in an additional cohort.

The paper assembles over 56,000 metagenome-assembled genomes from oral microbiome samples, revealing new taxa and biomarkers for diseases.

This paper presents a 3D printed microheater integrated microneedle patch system for controlled drug delivery, demonstrating its integration with wearable electronics for pain management.

This study identifies 26 gut microbiome biomarkers associated with schizophrenia and links specific bacterial species, like Streptococcus vestibularis, to altered neurotransmitter levels and behavioral changes in mice.

This study analyzes the vagino-cervical microbiome of 516 women using metagenomic shotgun sequencing to explore how pregnancy, delivery, and contraception influence microbiome composition.

The paper analyzes gene panel sequencing data from 829 Chinese high-risk breast cancer patients to identify pathogenic variants and variants of uncertain significance across 115 hereditary cancer susceptibility genes.

This study shows that PLEKHO1 in osteoblasts worsens joint inflammation in RA and promotes bone formation, suggesting it as a therapeutic target.

This paper shows that combining drugs targeting multiple ageing pathways in C. elegans can double lifespan and improve healthspan, with potential for human applications.