Author

M. Kamat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

K. B. Basso· 4 shared A. Creasy-Marrazzo· 2 shared A. I. Khan· 2 shared B. J. Shapiro· 2 shared E. J. Nelson· 2 shared E. T. Cato· 2 shared F. Qadri· 2 shared L. S. Bailey· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersMicrobiology

K. B. Basso

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Lipoxin A4/FPR2 signaling mitigates ferroptosis of alveolar epithelial cells via NRF2-dependent pathway during lung ischemia-reperfusion injury

D. Manual, V. Leroy, Z. Tu, M. Woolet-Stockton, M. Kamat, T. Garrett, C. Atkinson, G. Cai, G. R. Upchurch, A. K. Sharma

This study shows that LxA4/FPR2 signaling reduces ferroptosis in alveolar epithelial cells via NRF2 activation, protecting against lung ischemia-reperfusion injury.

bioRxiv · Apr 22, 2024Immunology

Genomic diversity of novel strains of mammalian gut microbiome derived Clostridium XIVa strains is driven by mobile genetic element acquisition

M. Kamat, M. J. Ormsby, S. Humphrey, S. K. Dixit, K. Thummler, C. Lapsley, K. Crouch, C. Jukes, H. Hulme, R. Burchmore, L. Meikle, L. Pritchard, D. M. Wall

The paper isolates and characterizes novel Clostridium XIVa strains from the murine gut, revealing genomic diversity driven by mobile genetic element acquisition and expanded biosynthetic potential.

bioRxiv · Jan 22, 2024 · PreprintMicrobiology

Phage predation, disease severity and pathogen genetic diversity in cholera patients

N. Madi, E. T. Cato, M. A. Sayeed, A. Creasy-Marrazzo, A. Cuenod, K. Islam, M. I. U. Khabir, M. T. R. Bhuiyan, Y. Begum, E. Freeman, A. Vustepalli, L. Brinkley, M. Kamat, L. S. Bailey, K. B. Basso, , E. J. Nelson

A study of cholera patients in Bangladesh identifies phage predation as a biomarker of disease severity and driver of coevolution within patients.

bioRxiv · Jun 14, 2023Microbiology

Generation and characterization of two immortalized dermal fibroblast cell lines from the spiny mouse (Acomys)

M. N. Dill, M. Tabatabaei, M. Kamat, K. B. Basso, C. S. Simmons

The paper generates and characterizes two immortalized dermal fibroblast cell lines from the spiny mouse to facilitate research on regeneration mechanisms.

bioRxiv · Dec 23, 2022Cell Biology

Piperlongumine (PL) conjugates induce targeted protein degradation

J. Pei, Y. Xiao, X. Liu, W. Hu, A. Sobh, Y. Yuan, S. Zhou, N. Hua, S. G. Mackintosh, X. Zhang, K. B. Basso, M. Kamat, Q. Yang, J. D. Licht, G. Zheng, , D. Lv

The paper identifies piperlongumine as a covalent E3 ligase recruiter that, when conjugated with CDK9 inhibitors, induces targeted protein degradation of CDK9 and EML4-ALK fusion oncoprotein.

bioRxiv · Jan 21, 2022Cancer Biology

Genome-wide association studies reveal distinct genetic correlates and increased heritability of antimicrobial resistance in Vibrio cholerae under anaerobic conditions

A. Creasy-Marrazzo, M. M. Saber, M. Kamat, L. S. Bailey, L. M. Brinkley, E. T. Cato, Y. A. Begum, M. M. Rashid, A. I. Khan, F. Qadri, K. B. Basso, B. J. Shapiro, E. J. Nelson

This study shows that antimicrobial resistance in Vibrio cholerae increases under anaerobic conditions and identifies distinct genetic factors associated with resistance in these conditions.

bioRxiv · Jun 26, 2021 · PreprintMicrobiology