R. Wu

The study analyzes the urinary microbiota of 147 Chinese women, revealing non-sterile urine with distinct bacterial communities and showing similarity to cervical and uterine microbiota rather than vaginal microbiota.

The paper maps root-microbe interactions in Arabidopsis thaliana by identifying host genetic variants and microbial hubs that influence microbial network structures and functions.

The paper shows tobacco carcinogens increase ACE2 mRNA but reduce ACE2 protein levels via Skp2-mediated ubiquitination, decreasing SARS-CoV-2 infection in lung cells.

This study analyzes cerebrospinal fluid from healthy pregnant women and finds no evidence of a detectable microbial community after accounting for contamination.

This study identifies a linear epitope on SARS-CoV-2 S-RBD recognized by a potent neutralizing antibody and shows its potential for vaccine design.

This paper develops a fluorescent chemodosimeter to visualize and isolate iron-reducing microorganisms at the single-cell level, demonstrating its effectiveness in identifying active FeRM from complex samples.

This paper introduces a rapid screening system to identify potent neutralizing antibodies against SARS-CoV-2 and demonstrates its effectiveness in discovering high-potency antibodies.

The paper shows that the interaction between UTX and DNMT1 regulates diet-induced myogenic remodeling in brown fat by maintaining brown adipocyte identity and thermogenic function.

The study uses mass cytometry to analyze immune cell subsets in convalescent COVID-19 patients, linking monocyte and T cell populations to disease severity and clinical markers.

This study identifies NTF3 as a fat-derived neurotrophic factor that regulates sympathetic innervation and thermogenesis in adipose tissue, influencing energy metabolism and obesity.

This study shows that polyamine homeostasis in T cells is regulated by de novo synthesis and salvage pathways, affecting proliferation and function, with implications for inflammatory and autoimmune diseases.

The paper uses single-cell RNA sequencing to analyze stomatal lineage cell development in Arabidopsis, identifying new marker genes and transcriptional networks.

This paper introduces a high-throughput drug screening method called CEBIT that detects biomolecular interactions and enzyme inhibitors by using phase-separated compartments.

This study analyzes 2,152 antibody repertoires to identify key features of B cell biology, revealing gene usage patterns, sex preferences, and mutability mechanisms in the antibody repertoire.

This study shows that ApoA1 deficiency impairs Treg cell homeostasis and function through reduced IL-2 signaling and altered cholesterol content in mice.

This study identifies immune-related genes under positive selection in schizothoracine fish, linking their adaptive evolution to speciation and local adaptation on the Qinghai-Tibetan Plateau.

The paper identifies 24,000 soil viral sequences and their hosts, revealing new viral diversity and roles in carbon metabolism across soil ecosystems.

The paper investigates pre-existing adaptive immune responses to CRISPR Cas proteins and AAVs in non-human primates and finds such immunity is普遍存在 regardless of Cas proteins or AAVs.

This study identifies G-quadruplex-forming regions in human ribosomal RNA, specifically in Expansion Segment 7, and shows their presence in chordate LSU rRNA.

This study identifies circZKSCAN1 as a negative regulator of cancer stem cells in hepatocellular carcinoma, revealing its mechanism through interaction with FMRP and CCAR1-Wnt signaling.

This study identifies and genotypes Trichosporon species isolated from giant pandas, finding 11 species with varying pathogenicity and genotypes.

The paper shows CCL3 promotes B cell interactions with follicular regulatory T cells in germinal centers, enhancing their negative regulation.

This study characterizes BaaR, an IclR-family repressor in Brucella abortus, showing it represses carboxylic acid oxidation operons and is activated by specific organic molecules.