S. Banerjee

This study compares metabolic reprogramming in the right ventricle of two rat models of severe pulmonary hypertension-induced right ventricular failure, identifying common and distinct metabolic signatures.

This study identifies an evolutionarily conserved 'E-L-L' motif in the SARS-CoV-2 spike protein as a target for small molecule fusion inhibitors, showing posaconazole effectively blocks viral entry across variants.

This study develops a theoretical model to show how actin filament length heterogeneity is regulated by nucleation and growth rate modulation by actin binding proteins, leading to distinct filament subpopulations.

This study characterizes TIR-199, a proteasome inhibitor that effectively targets myeloma and shows in vivo activity against bone degeneration.

The paper investigates thermotolerance variation in hybrid swordtail fish using genomic and transcriptomic analyses, finding reduced thermotolerance in hybrids due to genomic regions and misexpression of thermal stress genes.

The paper investigates how bacterial cell shape changes under antibiotic stress, showing that reducing surface-to-volume ratio decreases intracellular antibiotic concentration and enhances resistance.

This study identifies miR-573 as a regulator of endothelial dysfunction in dengue infection, showing it reduces permeability and inflammation by targeting ANGPT2 and TLR2.

This study uses AFM-IR to reveal structurally distinct polymorphs in tau aggregates, showing different secondary structures and antiparallel beta sheets in mature fibrils.

The paper identifies Ca2+-dependent liquid-liquid phase separation in CASQ1, a Ca2+ binding protein in skeletal muscle, explaining Ca2+ buffering and storage mechanisms.

This study compares clonal evolution across right-sided colon cancer, left-sided colon cancer, and rectal cancer patients, finding differences in evolutionary patterns and identifying polyclonal origins of lymph node and extranodal tumor deposits.

This study shows dystrophin loss disrupts the RhoA-actin-SRF pathway, leading to circadian dysregulation in muscle and peripheral tissues.

This study identifies DNA methylation changes in PDAC associated with disease severity and finds concordance with TCGA-PAAD and GTEx datasets.

This study investigates how chaperones modulate talin mechanics under single-molecule resolution, showing they alter unfolding forces and energy landscapes.

This study determines the structure of SARS-CoV-2 ExoN and its interaction with nsp10, revealing mechanisms of RNA substrate binding and exoribonuclease activity.

The paper finds that Bacillus subtilis maintains a robust surface-to-volume scaling relation under nutrient changes, regulated by nutrient-dependent cell division inhibitors.

The paper constructs a multi-scale agent-based model to study cell competition in epithelia, finding that mechanical competition depends on homeostatic density differences while biochemical competition depends on tissue organisation.

The paper identifies a feedback loop between RhoA and E-cadherin that drives asymmetric vertex motion in epithelial tissues through tension and frictional drag.

This study develops a reaction-diffusion model to investigate how mechanochemical feedback in the actin cortex generates pulsatile contractions and pattern formation.

This study shows that a high-fat diet in pancreatic cancer mice increases resistance to chemotherapy by promoting microbial metabolites like queuosine, which protect tumors through PRDX1 upregulation, and this resistance can be reversed by S-adenosyl methionine.

This study identifies and characterizes the Leishmania major Cu-ATPase, LmATP7, and demonstrates its role in copper stress resistance and parasite survival within macrophages.

This study shows clerodin induces mitotic abnormalities, G2/M arrest, and polyploidy in cells, similar to colchicine, through microtubule destabilization and shared binding site interaction.

This study shows that stromal IL6 promotes stem-like cells and metabolic reprogramming in pancreatic tumors, creating an immune-evasive microenvironment that can be targeted to improve checkpoint inhibitor therapy.

The paper uses magnetic-tweezers to study how chaperones respond to mechanical force, revealing their roles in generating or consuming energy during protein folding.

The paper reports higher CD8 and CD4 gene expression in the uterus of pregnant ewes compared to non-pregnant ewes, suggesting their potential as markers for pregnancy detection in sheep.

This study shows that soil microbial diversity loss reduces the temporal stability of ecosystem functions, with asynchrony among microbial taxa playing a key role.

This study shows that Leishmania infection causes hepcidin-mediated proteasomal degradation of Nramp1, increasing phagolysosomal iron availability and promoting parasite growth.

This study shows cholesterol in membranes enhances Aβ42 aggregation at low concentrations through AFM imaging and computational modeling.

This paper develops a copper-graphene nanocomposite transparent coating with antiviral activity against influenza virus, showing rapid inactivation of virions and reduced viral replication.