Author

S. Cole

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 2 Cell Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 7 Research Focus:cell type annotation· 5 Research Focus:differential expression· 5 Approach:experimental assay· 5 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1

Frequent Co-Authors

A. Lledo Lara· 2 shared A. Maroof· 2 shared F. Penkava· 2 shared N. Yager· 2 shared P. Bowness· 2 shared A. Cazenave-Gassiot· 1 shared A. Jalihal· 1 shared A. K. Sood· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

A. Lledo Lara

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Cellular metabolic state controls mitochondrial RNA kinetics

Sean D. Reardon, Clarisa Bautista, S. Cole, Julien Cicero, Tatiana V. Mishanina

The paper investigates how glucose deprivation affects mitochondrial RNA stability and transcription, revealing a metabolic link to mitochondrial gene regulation.

bioRxiv · May 13, 2025 · PreprintMolecular Biology

Differences in systemic immune parameters in individuals with lung cancer according to race

M. S. von Itzstein, J. Liu, H. Mu-Mosley, F. J. Fattah, J. Y. Park, J. A. SoRelle, J. D. Farrar, M. E. Gwin, D. Hsiehchen, Y. Gloria-Mccutchen, E. K. Wakeland, S. Cole, S. Bhalla, R. Kainthla, I. Puzanov, , D. E. Gerber

The paper compares systemic immune parameters between Black and White lung cancer patients, finding significant differences in cytokine levels and immune cell populations.

bioRxiv · Jun 7, 2024 · PreprintCancer Biology

Biomolecular condensates in fungi are tuned to function at specific temperatures

B. M. Stormo, G. McLaughlin, L. Frederick, A. Jalihal, S. Cole, I. Seim, F. Dietrich, A. S. Gladfelter

The paper shows that temperature affects the material properties of Whi3 condensates in fungi, which are optimized by sequence changes for specific climates.

bioRxiv · Nov 27, 2023Cell Biology

Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs

T. V. Cornforth, N. A. Moyo, S. Cole, E. Lam, T. Lobry, R. Wolchinsky, A. Lloyd, K. Ward, E. M. Denham, G. S. Besra, N. Veerapen, P. T. Illing, J. P. Vivian, J. M. Raynes, J. Le Nours, , J. Dukes

The paper shows that MR1-restricted TCRs recognize an allelic variant of MR1 (MR1*04) present in healthy individuals, indicating that these TCRs are not cancer-specific and may react to both cancer and healthy cells.

bioRxiv · Jul 17, 2023Cancer Biology

Ex vivo mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid

N. Yager, S. Cole, A. Lledo Lara, A. Maroof, F. Penkava, J. Knight, P. Bowness, H. Al-Mossawi

The paper uses mass cytometry and transcriptomic analysis to identify proinflammatory myeloid cell signatures in psoriatic arthritis synovial fluid.

bioRxiv · Mar 4, 2021Immunology

Ovarian Tumor Mitochondria Exhibit Abnormal Phenotypes and Blunted Associations with Biobehavioral Factors

S. Bindra, M. A. McGill, M. K. Triplett, A. Tyagi, P. H. Thaker, L. Dahmoush, M. J. Goodheart, T. Ogden, E. Owusu-Ansah, K. Karan, S. Cole, A. K. Sood, S. K. Lutgendorf, M. Picard

The paper examines mitochondrial content and function in ovarian tumors and their associations with biobehavioral factors, finding abnormal mitochondrial phenotypes and weaker biobehavioral correlations in tumors.

bioRxiv · Feb 26, 2021Cancer Biology

FasR regulates fatty acid biosynthesis and is essential for virulence of Mycobacterium tuberculosis

S. Mondino, C. L. Vazquez, M. Cabruja, C. Sala, A. Cazenave-Gassiot, F. C. Blanco, M. R. Wenk, S. Cole, F. Bigi, H. Gramajo, G. Gago

This study identifies FasR as a regulator of lipid metabolism in Mycobacterium tuberculosis, showing its essential role in virulence and immune evasion.

bioRxiv · Jun 8, 2020Microbiology

Single-cell sequencing reveals a clonal expansion of pro-inflammatory synovial CD8 T cells expressing tissue homing receptors in psoriatic arthritis

F. Penkava, M. Del Castillo Velasco-Herrera, M. D. Young, N. Yager, A. Lledo Lara, C. Guzzo, A. Maroof, L. Mamanova, S. Cole, M. Efremova, D. Simone, C. C. Brown, A. L. Croxford, S. Teichmann, P. Bowness, , M. H. Al-Mossawi

The paper identifies clonal expansion of pro-inflammatory CD8 T cells in psoriatic arthritis joints using single-cell sequencing and links them to tissue homing receptors and antigen specificity.

bioRxiv · Jul 16, 2019Immunology