Author

Scott McCroskey

Stowers Institute for Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:yeast· 4 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Jay R. UnruhiD· 2 shared Jeffrey J. LangeiD· 2 shared Laurence A. FlorensiD· 2 shared Alex T. Von SchulzeiD· 1 shared Alexandria J. CockrelliD· 1 shared Andrew Price· 1 shared Ann M. Cavanaugh· 1 shared Arvind RamanathaniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Jay R. UnruhORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Nascent protein retention at polysomes reduces kinetic barriers to self-assembly

Shriram Venkatesan, Alex T. Von Schulze, Jeffrey J. Lange, Jacob Jensen, Lexie E. Berkowicz, Dai Tsuchiya, Ning Zhang, Jennifer Gardner, Scott McCroskey, Ying Zhang, Selene K. Swanson, Yan Hao, Malcolm E. Cook, Tong Shu, Liam J. Holt, , Randal Halfmann

The paper shows that increasing translation initiation rates accelerates nucleation of aggregating proteins at polysomes, suggesting cotranslational nucleation influences proteome evolution.

bioRxiv · May 19, 2026 · PreprintCell Biology

Pericentromeric repeat copy number tunes heterochromatin dosage to control chromosome segregation and gene expression in fission yeast

Sarah E. Gilmour, Brandon L. Fagen, Devika Salim, María Angélica Bravo Núñez, Jeffrey J. Lange, Christopher Wood, Andrew Price, Michael T. Eickbush, R. Blake Billmyre, Alexandria J. Cockrell, Scott McCroskey, Martin Searcy, Kobe Koren, Luis Felipe Ramirez-Sanchez, Jennifer L. Gerton, Sarah E. Zanders

The paper investigates how pericentromeric repeat copy number affects chromosome segregation and gene expression in fission yeast by analyzing natural variation and engineered strains.

bioRxiv · May 12, 2026 · PreprintGenetics

Proteome plasticity in response to persistent environmental change

Matthew Domnauer, Fan Zheng, Liying Li, Yanxiao Zhang, Catherine E. Chang, Jay R. Unruh, Juliana Conkright-Fincham, Scott McCroskey, Laurence A. Florens, Ying Wen Zhang, Christopher W. Seidel, Benjamin Fong, Birgit Schilling, Rishi B. Sharma, Arvind Ramanathan, , Chuankai Zhou

This study shows that budding yeast adapts to long-term high temperature by reducing temperature-sensitive proteins, relocalizing the proteome, and altering protein conformations, which may confer new functions.

Molecular Cell · Jul 21, 2021Peer-reviewedMolecular Biology

The role of gene dosage in budding yeast centrosome scaling and spontaneous diploidization

Jingjing Chen, Zhiyong Xiong, Danny E. Miller, Zulin Yu, Scott McCroskey, William D. Bradford, Ann M. Cavanaugh, Sue L. Jaspersen

The paper investigates how gene dosage affects centrosome scaling and diploidization in budding yeast, linking ploidy changes to structural incompatibilities and evolutionary adaptations.

PLoS Genetics · Dec 17, 2020Peer-reviewedGenetics