Author

Stuart Newman

University of Essex

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

Leonard C. SchalkwykiD· 2 shared Adam R. SmithiD· 1 shared Alba Gomez-SeguraiD· 1 shared Alessia GambadoroiD· 1 shared Allan BradleyiD· 1 shared Amie Creighton· 1 shared Andreas Hörlein· 1 shared Ann‐Marie MalloniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Leonard C. SchalkwykORCID

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Author profile →

3 papers

Recent·Most cited

Reliable repurposing of the antibody interactome inside the cell

Caitlin M. O’Shea, Rushba Shahzad, Kimia Aghasoleimani, Stuart Newman, Jiraporn Panmanee, Leonard C. Schalkwyk, Greg Nicholas Brooke, Fiona E. Benson, James S. Trimmer, Daryl A. Bosco, Takao Fujisawa, Hidenori Ichijo, Neil R. Cashman, Stanislav Engel, Gareth S. A. Wright

The paper develops methods to improve the solubility and stability of intrabodies by optimizing linker design, domain orientation, and charge properties, enabling effective intracellular targeting of cytoplasmic proteins.

Nature Communications · Jan 31, 2026Peer-reviewedMolecular Biology

A resource of targeted mutant mouse lines for 5,061 genes

Marie‐Christine Birling, Atsushi Yoshiki, David J. Adams, Shinya Ayabe, Arthur L. Beaudet, Joanna R. BOTTOMLEY, Allan Bradley, Steve D. M. Brown, Antje Bürger, Wendy Bushell, Francesco Chiani, Hsian-Jean Genie Chin, Skevoulla Christou, Gemma F. Codner, Francesco John DeMayo, , Sandy Teichmann

The paper reports the generation of over 5,000 new mouse mutant strains for targeted genes, significantly expanding the available genetic resources for biomedical research.

Nature Genetics · Apr 1, 2021Peer-reviewedGenetics

A histone acetylome-wide association study of Alzheimer’s disease: neuropathology-associated regulatory variation in the human entorhinal cortex

Sarah J. Marzi, Szi Kay Leung, Teodora Ribarska, Eilis J. Hannon, Adam R. Smith, Ehsan Pishva, Jérémie Poschmann, Karen Moore, Claire Troakes, Safa Al‐Sarraj, Stephan Beck, Stuart Newman, Katie Lunnon, Leonard C. Schalkwyk, Jonathan S. Mill

This study identifies widespread H3K27ac acetylomic variation in AD cases compared to controls, linking it to disease-related pathways and AD-associated genetic variants.

Nature Neuroscience · Oct 11, 2018Peer-reviewedGenomics