Author

T. Matano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:chicken / avian· 1 Organism:human· 1

Frequent Co-Authors

H. Yamamoto· 3 shared T. Nomura· 3 shared H. Ishii· 2 shared T. Suzuki· 2 shared Y. Ami· 2 shared Y. Suzaki· 2 shared A. Kawana-Tachikawa· 1 shared A. Urakami· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

H. Yamamoto

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

CD34-positive monocytes are highly susceptible to HIV-1

N. Takahashi, O. Noyori, Y. Komohara, Y. M. Eltalkhawy, M. Hirayama, R. Yoshida, H. Nakayama, M. J. Kuroda, T. Nomura, H. Ishii, T. Matano, H. Gatanaga, S. Oka, M. Takiguchi, S. Suzu

This study identifies CD34+ monocytes as highly susceptible to HIV-1 infection, showing they harbor more proviral DNA and express higher HIV-1 receptors despite cART.

bioRxiv · Feb 26, 2024 · PreprintImmunology

A Tetravalent Dengue Virus-like Particle Vaccine Induces High levels of Neutralizing Antibodies and Inhibits Dengue Replication in Non-Human Primates

D. Thoresen, K. Matsuda, A. Urakami, M. M. Ngwe Tun, T. Nomura, M. L. Moi, Y. Watanabe, M. Ishikawa, T. T. T. Hau, H. Yamamoto, Y. Suzaki, Y. Ami, J. F. Smith, T. Matano, K. Morita, W. akahata

A tetravalent dengue VLP vaccine induces neutralizing antibodies and reduces viral replication in non-human primates without ADE.

bioRxiv · Oct 16, 2023Microbiology

SIV-specific neutralizing antibody induction following selection of a PI3K drive-attenuated nef variant

H. Yamamoto, T. Matano

This study shows that a PI3K drive-attenuated nef mutation in SIV leads to SIV-specific neutralizing antibody induction in infected macaques.

bioRxiv · Apr 19, 2023Immunology

Subacute SARS-CoV-2 replication can be controlled in the absence of CD8+ T cells in cynomolgus macaques

T. Nomura, H. Yamamoto, M. Nishizawa, T. Hau, S. Harada, H. Ishii, S. Seki, M. Nakamura-Hoshi, M. Okazaki, S. Daigen, A. Kawana-Tachikawa, N. Nagata, N. Iwata-Yoshikawa, N. Shiwa, S. Iida, , T. Matano

This study shows that subacute SARS-CoV-2 replication can be controlled without CD8+ T cells in cynomolgus macaques, suggesting CD8+ T-cell dysfunction may not solely cause viral control failure.

bioRxiv · May 26, 2021Microbiology

Multidrug treatment with nelfinavir and cepharanthine against COVID-19

H. Ohashi, K. Watashi, W. Saso, K. Shionoya, S. Iwanami, T. Hirokawa, T. Shirai, S. Kanaya, Y. Ito, K. S. Kim, K. Nishioka, S. Ando, K. Ejima, Y. Koizumi, T. Tanaka, , T. Wakita

This study identifies a new multidrug combination treatment for COVID-19 using nelfinavir and cepharanthine, showing synergistic antiviral effects and improved disease control.

bioRxiv · Apr 14, 2020 · PreprintMicrobiology