Author

Z. F. Fu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 5

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

B. Sui· 2 shared F. Guo· 2 shared G. Peng· 2 shared H. Chen· 2 shared L. Lv· 2 shared L. Zhao· 2 shared M. Zhou· 2 shared Q. Wu· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

B. Sui

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A spatial and cellular distribution of neurotropic virus infection in the mouse brain revealed by fMOST and single cell RNA-seq

Y. Zhang, X. Xing, B. Long, Y. Cao, S. Hu, X. Li, Y. Yu, D. Tian, Z. Luo, B. Sui, W. Liu, L. Lv, Q. Wu, J. Dai, M. Zhou, , L. Zhao

This study uses fMOST and scRNA-seq to map the spatial and cellular distribution of rabies virus in the mouse brain, revealing infection in multiple nuclei and non-neuronal cells.

bioRxiv · Mar 26, 2021Microbiology

Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteins

Y. Shi, J. Shi, L. Sun, Y. Tan, G. Wang, F. Guo, G. Hu, Y. Fu, Z. F. Fu, S. Xiao, G. Peng

This study compares the immunogenicity of spike proteins from Alpha- and Beta-coronaviruses, finding that Beta-CoVs induce stronger neutralizing antibodies against RBD than Alpha-CoVs.

Journal of Virology · Mar 10, 2021Peer-reviewedMicrobiology

The Preclinical Inhibitor GS441524 in Combination with GC376 Efficaciously Inhibited the Proliferation of SARS-CoV-2 in the Mouse Respiratory Tract

Y. Shi, L. Shuai, Z. Wen, C. Wang, Y. Yan, Z. Jiao, F. Guo, Z. F. Fu, H. Chen, Z.-G. Bu, G. Peng

This paper evaluates the antiviral efficacy of GS441524 and GC376 combination therapy against SARS-CoV-2 in a mouse model, showing synergistic effects and protection with low-dose combined treatment.

bioRxiv · Nov 12, 2020Microbiology

Reprogramming the endogenous type III-A CRISPR-Cas system for genome editing, RNA interference and CRISPRi screening in Mycobacterium tuberculosis

K. Rahman, M. Jamal, X. Chen, W. Zhou, B. Yang, Y. Zou, W. Xu, Y. Lei, C. Wu, X. Cao, R. Tyagi, M. A. Naeem, D. Lin, Z. Habib, N. Peng, , G. Cao

This paper reprograms the endogenous CRISPR-Cas10 system in Mycobacterium tuberculosis for efficient gene editing, RNA interference, and genome-wide screening, enabling functional genomics studies and drug/vaccine development.

bioRxiv · Mar 9, 2020 · PreprintMicrobiology

A novel antiviral lncRNA EDAL shields a T309 O-GlcNAcylation site to promote EZH2 degradation

L. Zhao, B. Sui, D. Chen, W. Liu, Q. Wu, B. Tian, J. Hou, Y. Li, S. Liu, J. Xie, H. Jiang, Z. Luo, L. Lv, F. Huang, R. Li, , Y. Zhang

This paper identifies a long non-coding RNA, EDAL, that inhibits neurotropic viruses by promoting EZH2 degradation through O-GlcNAcylation site interference.

bioRxiv · Oct 30, 2019 · PreprintMicrobiology