Z. Huang

This study investigates the PK/PD relationship of tilmicosin against M. hyopneumoniae, identifies resistance mechanisms, and suggests optimal dosing regimens.

This paper develops an acoustogenetic method using focused ultrasound to control CAR T cells, enabling noninvasive activation to treat cancer with reduced off-tumor effects.

This study profiles single-cell epigenomic and transcriptomic data from Parkinson's disease mouse brain to identify early biomarkers and cellular contributions to disease pathology.

This study uses ultra-deep sequencing to analyze clonal mutations in sun-exposed and non-sun-exposed skin, finding higher UV-signature mutations and mutation burden in sun-exposed samples.

The paper shows STAT3 localizes in mitochondria-associated ER membranes, not mitochondria, and other mitochondrial TFs also localize to MAMs.

The paper evaluates three 16S rRNA sequencing protocols for vaginal microbiome analysis and identifies biases in species abundance estimation, proposing an optimized protocol to improve accuracy.

This study identifies riboflavin as a direct mediator of electron transfer in microbial P450 monooxygenase dealkylation, revealing a novel mechanism involving FAD/FMN cofactors.

The paper shows that stress-induced myonectin improves glucose homeostasis by inhibiting glycemic response to epinephrine and enhancing insulin sensitivity in adipose tissues.

This study characterizes ovarian cancer spheroid phenotypes, identifies gene expression profiles linked to spheroid formation, and evaluates therapeutic responses of spheroids to various agents.

This study evaluates the mutant selection window and killing effects of five antibiotics against Mycoplasma hyopneumoniae, finding that danofloxacin, tylosin, and doxycycline are more likely to promote resistance than tiamulin and valnemulin.

The paper introduces a presuppositionless method to analyze single nanoparticle trajectories by leveraging their historical data, revealing spatiotemporal patterns without predefined models.

The paper identifies a molecular crosstalk where PD-L1 and CD80 form a heterodimer, blocking inhibitory pathways but preserving CD28 activation, and shows how PD-L1 blockade affects CD80 expression.

This paper introduces tunable optical elements for terahertz circular dichroism spectroscopy, enabling dynamic polarization modulation of THz radiation through mechanical strain.

This study investigates nasal immune responses in rainbow trout to Ichthyophthirius multifiliis infection, finding parasite-specific IgT production and B-cell proliferation in the nasal mucosa.

The paper shows that glutamic acid carries hydrazine during the biosynthesis of fosfazinomycin and kinamycin, forming an N-N bond through an acetylhydrazine intermediate.

This study shows that autophagy reduces lung injury by inhibiting the NF-κB pathway and inflammatory mediator release in hypoxia models.

This study shows miR-126 reduces S1PR2 expression, inhibits PI3K/AKT signaling, and impairs intestinal barrier function in IBD.