Z. Liang

This paper introduces SPACX, a method to profile protein conformation and interactions in living cells, revealing subcellular-specific heterogeneity and functional differences in PTEN.

The paper identifies ASGR1 as a potential receptor for SARS-CoV-2 that facilitates liver cell infection and suggests soluble ASGR1 as a therapeutic target.

This study develops allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv, showing enhanced anti-HIV activity in vitro compared to autologous CAR-T cells.

This paper investigates how different methods for measuring stem embolism vulnerability affect results, finding that nano-particles may induce early cavitation and that the origin of these particles might be from living cells near vessels.

This study examines the effects of losing RNA-directed DNA methylation in Setaria viridis by analyzing methylation patterns and gene expression in drm1ab mutants, finding limited morphological and transcriptional consequences.

This study shows that the Thr4 residue in the SrtA cleavage site of Streptococcus pyogenes M-protein evolved to ensure efficient SrtA cleavage over non-functional cleavage by LPXTGase, stabilizing the virulence factor on the cell wall.

This study uses electron microscopy to examine plastid conversion in Arabidopsis, showing CURT1A and CURT1C have distinct roles in etioplast to chloroplast development.

This paper introduces EEG-AVE, a model that combines EEG signals with audio-visual data to improve cross-individual affective detection performance.

The paper assesses chromatin accessibility and DNA methylation in four structurally diverse maize genomes, revealing conservation of features with dynamic boundaries in unmethylated regions.

This paper presents a hardware-software solution for co-registering photoacoustic tomography and MRI images in vivo, demonstrating hybrid-contrast imaging of tumor microenvironments.

This study characterizes the airway bacterial and fungal microbiome in COPD patients and healthy controls, finding altered microbial diversity and interactions associated with disease severity.

The paper uses transcriptome profiling of maize under heat and cold stress to identify cis-regulatory elements and develop models predicting gene expression responses.

The paper quantifies the phase separation properties of chromatin-associated proteins using an anti-1,6-hexanediol index and shows functional correlations with chromatin organization.

This paper reports a monoclonal antibody, 3E8, that blocks multiple coronaviruses by targeting ACE2, showing broad-spectrum activity against SARS-CoV-2 variants and other coronaviruses.

This study examines how genetic and epigenetic factors influence transposable element expression in maize under abiotic stress conditions.

The paper trains a classifier to predict cold stress transcriptional responses across plant species using genomic features, showing cross-species prediction accuracy.

The paper analyzes the airway microbiome in COPD patients at species and strain levels, revealing intra-genus diversity linked to inflammatory phenotypes and clinical outcomes.

This paper uses deep learning to estimate histological staining intensity from MRI signals, creating virtual histology maps of mouse brains with enhanced sensitivity and specificity.

This study develops an estrogen-inducible CRISPR/Cas9 system in Nicotiana tabacum and demonstrates its efficacy in inducing targeted mutagenesis of the NtPDS gene.

This study examines microbiome changes in lung and gut of NSCLC patients and finds sputum microbiota better predicts disease and metastasis than gut microbiota, with machine learning models achieving 0.842 AUC.

This study develops a reversed paired-gRNA plasmid cloning strategy to eliminate plasmid instability caused by direct repeats, achieving efficient genome editing in E. coli.

A CGMMV-based vector enables gene function studies in cucurbits, an extremely low efficiency species for genetic transformation.

The paper predicts and validates common neoantigens in colorectal cancer that are both presented and immunogenic, identifying potential universal targets for immunotherapy.

The paper phenotypes maize lines using conventional and hyperspectral imaging, showing correlations between image data and manual measurements, and highlights unique hyperspectral signatures in stem tissue.