Nicolas Girard

Specific dendritic cells spatial organization is associated to ICB Response in Non Small Cell Lung Cancer (NSCLC)

The paper examines the spatial organization of dendritic cell subsets in NSCLC patients treated with anti-PD1 and finds that cDC1-driven patterns correlate with prolonged ICB response.

Common origin for effector and regulatory Follicular and Tissue-Adapted CD4+ T cells in Non-Small Cell Lung Cancer

The paper identifies a common origin for effector and regulatory CD4+ T cells in non-small cell lung cancer through single-cell analysis, revealing their plasticity and role in immune responses.

Deep learning uncovers histological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients.

This study uses deep learning to predict YAP1/TEAD activity from histology slides, linking histological patterns to disease aggressiveness in cancer patients.

Radiotherapy triggers pro-angiogenic signaling in human lung

This study uses single-cell RNA sequencing to show that radiotherapy induces pro-angiogenic signaling in human lung tissue, including upregulation of VEGFA and changes in capillary and macrophage populations.