Author

Takehiro Suzuki

Tohoku UniversityORCID 0000-0002-1476-0794Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Chitose SuzukiiD· 2 shared Ken‐ichiro HayashiiD· 2 shared Takaaki AbeiD· 2 shared Takafumi ToyoharaiD· 2 shared Tetsuro MatsuhashiiD· 2 shared Yoshitsugu Oikawa· 2 shared Alexander TyshkovskiyiD· 1 shared Bohan ZhangiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Chitose SuzukiORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Non-DNA-damaging DNA-PK activation improving hearing and prolonging life due to NAD+ and SIRT upregulation

Yohei Honkura, Takehiro Suzuki, Ryota Kujirai, Shin-ichiro Kanno, Yotaro Matsumoto, Yoshikazu Tanaka, Kowit Hengphasatporn, Satoru Nagatoishi, Alexander Tyshkovskiy, Tomoko Kasahara, Yoshiyasu Tongu, Bohan Zhang, Hitomi Kashiwagi, Chika Saegusa, Msato Fujioka, , Takaaki Abe

This paper shows that MA-5 improves hearing loss and extends lifespan in mice by increasing NAD+ and SIRT1 through DNA-PK activation and mitochondrial function.

bioRxiv · Apr 18, 2025 · PreprintCell Biology

Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5

Yoshitsugu Oikawa, Rumiko Izumi, Masashi Koide, Yoshihiro Hagiwara, Makoto Kanzaki, Naoki Suzuki, Koichi Kikuchi, Tetsuro Matsuhashi, Yukako Akiyama, Mariko Ichijo, Shun Watanabe, Takafumi Toyohara, Takehiro Suzuki, Eikan Mishima, Yasutoshi Akiyama, , Takaaki Abe

This study identifies mitochondrial dysfunction in sporadic inclusion body myositis and shows that MA-5 improves mitochondrial function and protects myoblasts.

PLoS ONE · Dec 2, 2020Peer-reviewedNeuroscience