Maria Ermolaeva

Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging.

The paper identifies a decline in phosphatidylcholine synthesis as a driver of mitochondrial aging that can be reversed by dietary interventions in both worms and human cells.

Inactivation of the DREAM complex mimics the molecular benefits of sleep.

This study identifies the DREAM complex as a mediator of sleep and circadian benefits, showing that inhibiting DREAM can mimic sleep's cellular repair effects in sleep-deprived organisms.

Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging.

The paper compares liver proteomes of long-lived naked mole-rats and short-lived guinea pigs to identify molecular networks linked to longevity and human aging.