Tim S. Veth

Unifying N- and O-glycopeptide dissociation methods with expedient electron transfer dissociation

This paper improves ETD-based fragmentation for glycopeptide analysis by optimizing ion handling and scan parameters, making it faster and more efficient for both N- and O-glycopeptides.

Defining glycoproteoform landscapes through an integrated glycoproteomics approach enabled by high-resolving power proton transfer charge reduction tandem mass spectrometry

This paper introduces a high-resolving power DIA-PTCR method for glycoproteoform analysis, enabling isotopically resolved mass measurements and integration with other glycoproteomics approaches.

GlycoDiveR: a modular R framework to analyze and visualize highly dimensional glycoproteomics data

GlycoDiveR provides a modular R framework for analyzing and visualizing high-dimensional glycoproteomics data, improving accessibility and flexibility in glycosylation analysis.

Sialoglycans on human T cells attenuate death programs executed through the Fas pathway

This study shows that sialoglycans on human T cells reduce Fas receptor-mediated apoptosis but not other TNF receptor pathways.

Antibodies disrupt bacterial adhesion by ligand mimicry and allosteric interference

This study identifies four antibody mechanisms that disrupt FimH-mediated bacterial adhesion by altering its conformation and glycan binding.

Extracting informative glycan-specific ions from glycopeptide MS/MS spectra with GlyCounter

GlyCounter is a tool to extract glycan-specific ions from glycopeptide MS/MS spectra, enabling analysis of glycan features without database searches.

CD5L is a canonical component of circulatory IgM

The paper identifies CD5L as a component of circulatory IgM, showing it forms a complex with J-chain-containing pentamers and affects IgM receptor binding.

Elucidating Fibroblast Growth Factor-induced kinome dynamics using targeted mass spectrometry and dynamic modeling

The paper quantifies kinase activity dynamics in response to FGF ligands and uses dynamic modeling to reveal pathway regulation and novel kinase involvement.