Author

Masato Yasui

Keio UniversityORCID 0000-0002-5481-1779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jumpei SasabeiD· 2 shared Sakiko Taniguchi· 2 shared Takanori Kanai∥iD· 2 shared Akinori HashiguchiiD· 1 shared Alessandro UsielloiD· 1 shared Alexander Stanley ThraneiD· 1 shared Angela ChamberyiD· 1 shared Anna L. R. XavieriD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Jumpei SasabeORCID

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3 papers

Recent·Most cited

Chiral shift toward D-serine reflects intrathecal inflammation in multiple sclerosis and counteracts motor impairment in a murine model

Alessandro Usiello, Kenta Arisumi, Tommaso Nuzzo, Luana Gilio, Sakiko Taniguchi, Rosita Russo, Haruhiko Motegi, Raffaella di Vito, Junichi Hata, Francesco Errico, Akinori Hashiguchi, Hideyuki Okano, Roberto Furlan, Annamaria Finardi, Mario Stampanoni Bassi, , Jumpei Sasabe

The paper shows that O_SCPLOWDC_SCPLOW-serine levels are elevated in MS patients and mitigates motor deficits in a murine model.

bioRxiv · May 7, 2025 · PreprintNeuroscience

D-serine suppresses one-carbon metabolism by competing with mitochondrial L-serine transport

Masataka Suzuki, Kenichiro Adachi, Pattama Wiriyasermukul, Mariko Fukumura, Ryota Tamura, Yoshinori Hirano, Yumi Aizawa, Tetsuya Miyamoto, Sakiko Taniguchi, Masahiro Toda, Hiroshi Homma, Kohsuke Kanekura, Kenji Yasuoka, Takanori Kanai∥, Masahiro Sugimoto, , Jumpei Sasabe

This study shows D-serine competes with mitochondrial L-serine transport, suppressing one-carbon metabolism and affecting neural cell proliferation.

bioRxiv · Sep 3, 2024 · PreprintBiochemistry

Aquaporin-4 dependent glymphatic solute transport in rodent brain

Humberto Mestre, Lauren M. Hablitz, Anna L. R. Xavier, Weixi Feng, Wenyan Zou, Tinglin Pu, Hiromu Monai, Giridhar Murlidharan, Ruth M. Castellanos Rivera, Matthew J. Simon, Martin M. Pike, Virginia Plá, Ting Du, Benjamin T. Kress, Xiaowen Wang, , Maiken Nedergaard

This study confirms that AQP4 is essential for glymphatic fluid and solute transport in the rodent brain, as Aqp4 disruption reduces CSF influx and amyloid-beta efflux.

eLife · Dec 18, 2018Peer-reviewedNeuroscience