Author

Sakiko Taniguchi

Keio University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:human· 1

Frequent Co-Authors

Jumpei SasabeiD· 2 shared Masato YasuiiD· 2 shared Takanori Kanai∥iD· 2 shared Akinori HashiguchiiD· 1 shared Alessandro UsielloiD· 1 shared Angela ChamberyiD· 1 shared Anika P. WileniD· 1 shared Anis ContractoriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Jumpei SasabeORCID

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3 papers

Recent·Most cited

Chiral shift toward D-serine reflects intrathecal inflammation in multiple sclerosis and counteracts motor impairment in a murine model

Alessandro Usiello, Kenta Arisumi, Tommaso Nuzzo, Luana Gilio, Sakiko Taniguchi, Rosita Russo, Haruhiko Motegi, Raffaella di Vito, Junichi Hata, Francesco Errico, Akinori Hashiguchi, Hideyuki Okano, Roberto Furlan, Annamaria Finardi, Mario Stampanoni Bassi, , Jumpei Sasabe

The paper shows that O_SCPLOWDC_SCPLOW-serine levels are elevated in MS patients and mitigates motor deficits in a murine model.

bioRxiv · May 7, 2025 · PreprintNeuroscience

D-serine suppresses one-carbon metabolism by competing with mitochondrial L-serine transport

Masataka Suzuki, Kenichiro Adachi, Pattama Wiriyasermukul, Mariko Fukumura, Ryota Tamura, Yoshinori Hirano, Yumi Aizawa, Tetsuya Miyamoto, Sakiko Taniguchi, Masahiro Toda, Hiroshi Homma, Kohsuke Kanekura, Kenji Yasuoka, Takanori Kanai∥, Masahiro Sugimoto, , Jumpei Sasabe

This study shows D-serine competes with mitochondrial L-serine transport, suppressing one-carbon metabolism and affecting neural cell proliferation.

bioRxiv · Sep 3, 2024 · PreprintBiochemistry

A pathogenic missense mutation in kainate receptors elevates dendritic excitability and synaptic integration through dysregulation of SK channels

Toshihiro Nomura, Sakiko Taniguchi, Yizhi Wang, Nai-Hsing Yeh, Anika P. Wilen, Charlotte Castillon, Kendall M. Foote, Jian Xu, John N. Armstrong, Jeffrey N. Savas, Geoffrey T. Swanson, Anis Contractor

This study investigates a missense mutation in the GRIK2 gene, showing it disrupts SK channel function, leading to increased dendritic excitability and synaptic integration in hippocampal neurons.

Journal of Neuroscience · Oct 6, 2023Peer-reviewedNeuroscience