Author

Carisa Zeng

Washington University in St. LouisORCID 0000-0002-7108-3873Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

Maxim N. ArtyomoviD· 3 shared Aileen Lee· 1 shared Alina Ulezko AntonovaiD· 1 shared Andrew WangiD· 1 shared Björn SchumacheriD· 1 shared Chenyang Guan· 1 shared Darya KhantakovaiD· 1 shared David M. HoltzmaniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersPhysiology

Maxim N. ArtyomovORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cysteine reduction rather than methionine restriction promotes immunometabolic fitness to confer survival benefit in aging

Lucie Orliaguet, Hee‐Hoon Kim, Piyush Gupta, Aileen Lee, Yuanjiu Lei, Ruiqi Li, Carisa Zeng, Yun‐Hee Youm, Tamara Dlugos, Chenyang Guan, Andrew Wang, Maxim N. Artyomov, Yuval Kluger, Björn Schumacher, Vishwa Deep Dixit

This study shows that reducing cysteine, not methionine, improves immunometabolic fitness and extends healthy lifespan in aging organisms.

bioRxiv · Sep 9, 2026 · PreprintPhysiology

CD8+ T cells are primed by cDC1 and exacerbate tau-mediated neurodegeneration

Hao Hu, Peter Bor‐Chian Lin, Carisa Zeng, Prabal Sharma, Yongyi Li, Hong Jiang, Jonathan Nulman, Ray A. Ohara, Tong Wu, Shasha Li, Wayne M. Yokoyama, Maxim N. Artyomov, KENNETH M. M. MURPHY, Jason D. Ulrich, David M. Holtzman

This study shows that cDC1 cells prime CD8+ T cells, which then exacerbate tau-mediated neurodegeneration in mice.

bioRxiv · Mar 1, 2026 · PreprintNeuroscience

Myofibroblastic CAFs arising from bone-resident osteoblast precursors retain an osteolineage signature and support breast cancer progression via Osterix-mediated signaling.

Giulia Furesi, Carisa Zeng, Emily M. Eul, Deborah V. Novack, Junhua Ye, Vasilios Aris Morikis, Taylor Malachowski, Darya Khantakova, Alina Ulezko Antonova, Marco Colonna, Gregory D. Longmore, Sheila A. Stewart, Maxim N. Artyomov, Roberta Faccio

bioRxiv · Sep 18, 2025 · PreprintCancer Biology