Zafar Iqbal Bashir

Layer 5 lateral entorhinal cortex neurons encode updating of object-place associations

The paper identifies layer 5 lateral entorhinal cortex neurons as engram cells involved in object-place association memory and shows they update representations when environments change.

Medial prefrontal cortex input to lateral entorhinal cortex supports both encoding and retrieval of associative recognition memory

This study shows that a direct connection from medial prefrontal cortex to lateral entorhinal cortex is critical for associative recognition memory, depending on the memory retention delay.

Why do hippocampal mossy cells matter? It depends on the frequency and context.

This study shows mossy cells influence hippocampal function differently based on frequency and context, affecting memory and seizure risk.

Thalamic nucleus reuniens preferentially targets inhibitory interneurons over pyramidal cells in hippocampal CA1 region

The paper investigates the synaptic connections of the nucleus reuniens to hippocampal CA1 and finds that it preferentially targets inhibitory interneurons rather than pyramidal cells.

Sustained postsynaptic kainate receptor activation downregulates AMPA receptor surface expression and induces hippocampal LTD

This study shows that sustained kainate receptor activation reduces AMPA receptor surface expression and induces hippocampal long-term depression.

Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

This study identifies LRFN2 as a new SNX27-dependent cargo that regulates AMPA receptor trafficking and synaptic function, revealing an indirect mechanism for SNX27's role in neurological conditions.

Plasticity in prefrontal cortex induced by coordinated nucleus reuniens and hippocampal synaptic transmission

The paper investigates synaptic plasticity in the medial prefrontal cortex induced by coordinated nucleus reuniens and hippocampal inputs, showing distinct plasticity properties and a novel mechanism for circuit encoding.