Yingying Hu

TASOR expression in naive embryonic stem cells safeguards their developmental potential

This study identifies TASOR's role in maintaining developmental potential during the transition from naive to primed pluripotency by preventing L1 transposable element activation and subsequent cell death.

Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

This paper develops an engineered extracellular vesicles-based vaccine platform for combined mRNA and protein delivery, showing tumor regression and immune responses in preclinical models.

Enhance genome editing efficiency and specificity by a quick CRISPR/Cas9 system

This study introduces qCas9, a modified CRISPR/Cas9 system that enhances genome editing efficiency and reduces off-target effects in zebrafish and mammalian cells.