imaging

DigiFish: A flexible open-source tool for animating realistic virtual fish and reconstructing visual fields from tracking data

DigiFish creates realistic virtual fish animations and reconstructs visual fields from tracking data to study visually guided behavior.

Differential Adaptation of Osteocyte Lacunar Morphology at Bone (Re)modeling Sites under Mechanical Loading and Pharmacological Therapies in a Mouse Model of Osteoporosis

The paper examines how mechanical loading and pharmacological therapies affect osteocyte lacunar morphology in a mouse osteoporosis model, showing distinct adaptations in lacunar density, volume, and sphericity.

CelFDrive: Artificial Intelligence assisted microscopy for automated detection of rare events

CelFDrive automates high-resolution 3D imaging of cells using deep learning for efficient detection of rare events in large populations.

Patient-Derived Liver Cancer Organoids Reflect Tumor Biology and Their Growth Phenotype Correlates with Clinical Outcomes

Organoids grew from 13 of 27 resected hepatocellular carcinomas. The sequenced lines kept parental mutations, and solid rather than cystic growth marked shorter progression-free survival (HR 13.91).

Tracing the dynamic recruitment trajectory of Optineurin between the centrosome and other macromolecular assemblies, signifying its role in cell cycle progression

This study tracks Optineurin's movement between the centrosome and cytokinetic structures during cell division, revealing its microtubule-dependent trafficking and role in cell cycle progression.

4D confocal microscopy of time dependent cell and nuclear osmotic response reveals differential osmoregulation and transport kinetics

This study uses 4D confocal microscopy to quantify cell and nuclear volume changes under osmotic stress and estimates transport parameters.

Regional Similarity to Sex-Typical Young Adult Brain Architecture is a Longitudinal Correlate of Neuroinflammation and Depression in Later Adulthood

The paper examines how regional brain architecture similarity to sex-typical young adult patterns correlates with neuroinflammation and depression in later adulthood using longitudinal data.

Discovering Latent Scientific Concepts through Discrete Representation Learning

This paper introduces Kodiak, a discrete representation learning method for scientific imaging that improves representation quality and enables interpretable, reusable concepts across domains.

Wavelet Transform Coherence Under Controlled Temporal Correspondence and Social Co-Presence: Implications for fNIRS Hyperscanning

This study evaluates wavelet transform coherence (WTC) in fNIRS hyperscanning, showing it reliably detects temporal correspondence but is context-sensitive, particularly influenced by social co-presence.

Using a 3-step semi-automated image analysis pipeline to quantify differences in VE-cadherin junction morphology in lymphatic endothelial cells in vitro

This paper develops a 3-step image analysis pipeline to quantify VE-cadherin junction morphology in lymphatic endothelial cells, identifying new metrics that distinguish button-like and zipper-like junctions.

The Role of Retinal Flow in Walking

This study investigates how retinal flow affects walking trajectories in virtual reality, finding that ground-plane motion has a greater impact on path straightening than wall motion.

Learning fly pose from vision-language annotations

This paper uses a vision-language model to generate annotations for fruit fly pose estimation, achieving high accuracy and enabling efficient training of pose estimation networks.

Higher frequency of homologous chromosome pairing in adult endothelial cells as compared to neonatal endothelial cells

The paper compares homologous chromosome pairing in adult and neonatal endothelial cells, finding higher pairing frequency in adults.

Multiscale Network Disruption of Auditory-Language Circuits Underlying Auditory Hallucinations in Schizophrenia

This study identifies auditory-language network disruptions in schizophrenia linked to hallucination severity using fMRI and network analysis.

On-demand surround suppression explains the spatiotemporal window of the tilt illusion

The paper investigates the tilt illusion to show that perceptual context is actively gathered over time, not passively received, by demonstrating that more distant surrounds influence perception later.

The Walking Brain: Mapping feature-specific cortical responses to naturally unfolding sensory experience in the real world

This paper maps feature-specific cortical responses to real-world sensory experiences using wearable fNIRS during walking and movie viewing, showing spatial correspondence between luminance and sound maps.

A psychophysical characterization of tactile and temperature perception on the human torso

This study characterizes tactile and temperature perception on the human torso through psychophysical tests, revealing site-specific differences in pleasantness, intensity, and sensitivity.

Slice, Subtract, Segment: Efficient 2D and Physiologically Informed 3D Brain Tumor Segmentation

This paper evaluates two approaches for improving brain tumor segmentation: a novel 2D U-Net architecture and a multi-channel input representation using cross-modal subtraction maps, showing both contribute to performance improvements.

Mapping Mesolimbic Dopamine Projections to Subcortical Circuits Underlying Adaptive Behavior: A Human 7T Diffusion Tractography Atlas

The paper maps human mesolimbic dopamine pathways using 7T diffusion tractography, revealing distinct circuits and their associations with adaptive behaviors.

Biomechanical Compatibility With Physiological Limb-Flexion Deformation Reduces Inflammation and Neointimal Hyperplasia After Peripheral Stenting

This study shows that a stent designed to better accommodate limb-flexion deformation reduces inflammation and neointimal hyperplasia compared to a standard stent.

Extended high frequency hearing influences cortical response amplitudes to speech

This study shows that deficits in extended high-frequency hearing reduce cortical response amplitudes to speech, even in young adults, and highlights the need to include EHF hearing in clinical assessments and hearing aid design.

Facial color properties affect perceived age.

The paper investigates how facial color properties influence perceived age, finding that red-green contrast and redness levels affect youthfulness perception independently of luminance.

Carnivores in a metropolitan forest island: first spatial capture-recapture estimates reveal high densities of leopards and striped hyenas in Jaipur, India

The paper estimates leopard and striped hyena densities in an urban protected area using camera-traps and spatial capture-recapture models, finding high densities and significant temporal overlap.

Deep Learning-Meets-Active Surfaces: A Unified Framework for Multi-Object Segmentation and Shape Analysis in 3D Fluorescence Microscopy

This paper introduces Nagini3D, a 3D image segmentation method combining deep learning and active surfaces for improved shape analysis and consistency across 3D volumes.

NucLogic: Logic-based geometric 3D nuclear segmentation for fast and robust analysis of challenging biological imaging data

NucLogic provides a fast and robust 3D nuclear segmentation method that outperforms existing tools at low SNR and enables quantitative analysis of challenging biological imaging data.

Cholera toxin remodels intestinal immunity and suppresses systemic metabolism

This study shows that cholera toxin alone rapidly reorganizes intestinal immunity, epithelial, metabolic, and microbial environments while suppressing whole-body metabolism in mice.

Pathogenic DRP1 variants reveal a role for biomolecular condensation in mitochondrial fission

This study shows pathogenic DRP1 variants impair mitochondrial fission by affecting biomolecular condensation, revealing a new regulatory mechanism.

Functional deficits of the inhibitory control system in children with ADHD: A task-based fMRI meta-analysis

This study identifies reduced preSMA activation in children with ADHD during inhibitory control tasks using fMRI meta-analysis.

LABEL-FREE HEMODYNAMIC MAPPING VIA ULTRAFAST POWER DOPPLER-ENHANCED PHOTOACOUSTIC IMAGING REVEALS EARLY THERAPY-INDUCED FUNCTIONAL CHANGES IN THE TUMOR.

This study uses dual-modality imaging to assess therapy-induced changes in tumor vascular function and oxygenation, revealing spatial heterogeneity in response to photodynamic therapy.

BettaAI: a machine-learning object detection model for the quantification of aggressive displays in the Siamese fighting fish Betta splendens

BettaAI is a deep learning model that accurately detects and quantifies aggressive displays in Siamese fighting fish using video analysis.