imaging

Eye movement markers of relational encoding predict scene memory precision

This study shows that how gaze is organized during scene viewing, not just how much is viewed, predicts memory precision for scenes.

Inverse relationship between mitochondrial and non-coding nuclear DNA content in free-living kinetoplastids

The paper investigates the relationship between mitochondrial and non-coding nuclear DNA content in kinetoplastids, finding an inverse correlation that suggests co-evolution of genome sizes.

Thalamic Dysconnectivity and Negative Symptoms in Schizophrenia Spectrum Disorder

This study identifies thalamic dysconnectivity as a key feature of negative symptoms in schizophrenia spectrum disorder using structural and functional MRI data.

Cross-scale Imaging of Live Botanical Specimens using Fourier Ptychographic Microscopy

This paper applies Fourier ptychographic microscopy to label-free imaging of large botanical specimens, achieving high-resolution imaging over a large field of view.

Calcium-independent biosensors for multiplexed in vivo imaging of extracellular lactate dynamics

The paper develops Ca2+-independent lactate biosensors for multiplexed in vivo imaging of extracellular lactate dynamics alongside neuronal activity.

Quantifying antibiotic susceptibility and inoculum effects using transient dynamics of Pseudomonas aeruginosa

This paper develops a computational pipeline to quantify antibiotic susceptibility and inoculum effects in Pseudomonas aeruginosa by analyzing transient dynamics and identifying a novel mathematical model.

Communication as a Two-Person Neural Process: fNIRS Hyperscanning in Adults with and without Post-Stroke Aphasia

This paper uses fNIRS hyperscanning to study interbrain synchrony during communication in healthy adults and those with post-stroke aphasia, showing task-dependent neural coupling.

Psychedelics Restructure the Global Workspace of Consciousness

This study investigates how psychoactive drugs alter the global workspace of consciousness by analyzing resting-state fMRI data, finding distinct changes in synergistic and redundant interactions across drug types.

golgi: open-source software for automated nerve model generation and recruitment simulation

golgi automates nerve model generation and recruitment simulation from images, offering a scalable open-source platform with Python API and GPU acceleration.

Behavioral arousal organizes visual cortical population micro-states across the sleep-wake cycle

The paper shows that visual cortical population micro-states are organized by behavioral arousal rather than discrete sleep-wake states in mice.

Covalent Solvatochromic Membrane Probe for Sensing Lipid Surrounding of Proteins

This paper introduces a new fluorescent probe, MemGraft-NR, for sensing lipid organization around proteins, showing higher sensitivity to cholesterol and revealing new insights into protein-lipid interfaces in live cells and endosomes.

Evaluating low-cost hyperspectral and RGB fusion with PSNet for presymptomatic detection of Albugo candida in Arabidopsis thaliana

This paper evaluates PSNet, a multimodal framework combining hyperspectral and RGB imaging, for early detection of Albugo candida in Arabidopsis thaliana, showing high accuracy but no consistent advantage of hyperspectral fusion over RGB alone.

The Attentional Thief: Scrolling-Like Picture Streams Compress Subjective Time

This study investigates how scrolling-like picture streams affect subjective time perception, finding that self-paced viewing compresses perceived duration compared to passive viewing and a baseline condition.

Shared Fine-Scale Functional Organization in the Human Subcortex Revealed by Connectivity Hyperalignment

This paper introduces a method to align subcortical brain connectivity across individuals, revealing shared fine-scale functional organization that was previously obscured by anatomical variability.

Structure-function coupling in the human brainstem

This study reconstructs brainstem connectomes using MRI and finds structural and functional connectivity correlations, revealing heterogeneous structure-function coupling across brainstem nuclei.

Templated seeding induces the formation of Alzheimer paired helical tau filaments in human brain organoids

Cortical organoids from healthy human iPSCs, seeded with Alzheimer brain tau, form three-repeat tau filaments that cryo-EM shows are identical to Alzheimer paired helical filaments and need endogenous tau.

Cortical organoid diffusion MRI reveals protocol-associated spatial reproducibility and increasing apparent diffusivity with diffusion time

This study uses cortical organoids to examine diffusion MRI reproducibility and apparent diffusivity changes with diffusion time, finding increased apparent mean diffusivity in most tissue voxels.

Green Synthesis of Fluorescent Carbon Quantum Dots from Bearberry Extract via Hydrothermal and Microwave-Assisted Routes: Comparative Physicochemical Characterisation, Antioxidant Activity, and Biocompatibility Evaluation

This paper compares hydrothermal and microwave-assisted synthesis of carbon quantum dots from bearberry extract, showing how synthesis method affects surface chemistry, photophysical properties, and biological activity.

Fast single molecule localization microscopy in 3D

This paper introduces Intrinsic3D, a 3D SMLM method that enables rapid, whole-cell protein mapping with nanometre resolution, demonstrating its application in studying cell adhesion structures.

Lipocalin-2-expressing red pulp macrophages link ischemic stroke to systemic immune reprogramming in mice and humans

Splenic Lcn2 is induced biphasically after mouse stroke and localizes to red pulp macrophages; recombinant LCN2 induces T cell and monocyte hyporesponsiveness and monocyte phagocytosis-ROS uncoupling, with human spleen support.

Distinct Hippocampal Cellular Pathologies Influence Cognition Across Diagnostic Categories and Distinguish Schizophrenia from Affective Psychoses

This study identifies distinct hippocampal cellular pathologies associated with cognition in schizophrenia and affective psychoses, showing differences in metabolite biomarkers between these conditions.

AI-assisted quantification of the clonogenic assay

This paper develops an AI framework for automated clonogenic assay analysis, showing it matches expert performance and enables continuous phenotypic profiling of radioresistant cells.

Restoration of (nor)adrenergic-like Ca2+ signalling counteracts age-related motor decline

The paper shows that restoring noradrenergic-like Ca2+ signaling in aged Drosophila improves motor function and lifespan by enhancing metabolic responses.

Imputation-Based Harmonization Mitigates Site Effects Without Data Leakage in Machine Learning Studies

The paper introduces MIRTH, an imputation-based harmonization method that mitigates site effects in neuroimaging data without data leakage, achieving high predictive accuracy in machine learning studies.

Structural integrity moderates the cognitive bearing of dopamine clearance in aging

The paper develops ADAM, a model linking dopamine clearance and structural connectivity to cognitive aging, finding elevated clearance timescales and a structure-age-dependent association with cognitive performance.

Build it, But Did They Come? Monitoring Winter Feeding Stations Use by Endangered Long-tailed Gorals

The paper assesses how environmental and demographic factors influence feeding behavior of endangered long-tailed gorals at winter supplementary feeding stations.

Behavioral characterization of dynamic facial expression perception in rhesus monkeys (Macaca mulatta) using naturalistic and synthetic stimuli

This study shows rhesus monkeys can categorize facial expressions and generalize to novel stimuli, with performance influenced by expression components and signaler characteristics.

Unmasking Early Hepatorenal Fibrosis in Polycystic Kidney Disease Using Noninvasive Precision Molecular MRI of Collagen

This paper develops a collagen-targeting MRI contrast agent to noninvasively detect early fibrosis in ADPKD, showing improved detection compared to standard agents.

Predicting recovery trajectories and injury severity following partial crush spinal cord injury in mice

This paper predicts recovery trajectories and injury severity after partial crush spinal cord injury in mice using behavioral data and statistical modeling.

Fear Learning Induced Brain Dynamics Predict Individual Extinction Memory Expression following Transcranial Magnetic Stimulation

The paper shows that fear learning reorganizes brain activity, and this reorganization predicts extinction memory expression when modulated by TMS during extinction learning.