zebrafish

This study shows that a sensory reference for vocal learning is gated through the basal ganglia in songbirds, with HVC providing a temporally aligned tutor signal to Area X.

The paper identifies a new maternal cell type that enabled live-bearing and placentation in fish through evolutionary co-option of existing gene regulatory networks.

This study develops multivalent mRNA vaccines against tuberculosis using antigens identified in zebrafish, showing protection in mice, guinea pigs, and comparable efficacy to BCG.

The paper identifies RNA phase transitions during zebrafish oocyte-to-embryo transition using fractionation RNA-seq and machine learning, revealing ribosome-dependent and -independent mechanisms.

This study identifies distinct roles for Hip14 in regulating acoustic startle sensitivity and habituation through catalytic-dependent and -independent mechanisms in zebrafish neurons.

This study investigates mitochondrial remodeling and metabolic changes in zebrafish Muller glia during retinal regeneration, showing compartment-specific mitochondrial changes and the role of PDK/PDH regulation.

The paper introduces a zebrafish model and computational framework to systematically analyze cancer metastasis patterns across organs, revealing heterogeneity and spatial preferences in dissemination.

This study compares proteomic responses to lead exposure in house sparrows from two Australian towns, finding divergent molecular strategies in proteostasis and haem biosynthesis.

This study examines haploid-induced tissue defects in zebrafish larval eyes, revealing disorganized cellular structures and impaired photoreceptor and ganglion cell organization.

The paper investigates how B chromosomes in maize affect chromatin accessibility and gene expression in pollen nuclei using ATAC-seq and RNA-seq.

The paper shows zebrafish lack canonical necroptosis due to absence of MLKL, despite functional RIPK3, and demonstrates viability of Caspase-8-deficient zebrafish without necroptosis.

This study identifies HRG as a plasma biomarker of Ni-Cr exposure and reveals nuclear toxicity linked to DNA damage and epigenetic disruption in house sparrows.

This study shows that chronic FMNL2 overexpression in zebrafish causes brain histological changes and altered exploratory behavior similar to those seen after acute Aβ42 exposure.

This study shows that combining apple pectin and cellulose in zebrafish diets leads to non-additive gut microbiome changes and lasting intestinal barrier effects.

The paper introduces LADD to measure lineage path deviations from inferred developmental dynamics in single-cell RNA-seq data and finds lineages move faster than optimal paths.

This study identifies five novel ocular enhancers in zebrafish that regulate rax expression during eye development and shows their robustness to perturbations.

This study identifies the endothelial protein C receptor (EPCR) as the entry receptor for Langya virus and reveals the molecular basis of its interaction with the viral attachment glycoprotein.

The paper evaluates avian genome assemblies across geography and taxonomy, revealing underrepresentation of species in the Global South.

This study uses live imaging in zebrafish to show that hindbrain medulloblastoma cells spread more frequently than forebrain or midbrain tumors and that dasatinib reduces dissemination.

The paper investigates plumage diversity in Capuchino Seedeaters by analyzing gene expression and variants, finding that pigmentation differences arise from regulatory changes rather than differential gene expression.

The paper exposes zygnematophyte algae to UV irradiance and identifies conserved molecular responses, including lipid droplets and phenolic compounds, suggesting a shared UV acclimation mechanism with land plants.

The paper identifies a novel epithelial cell type in zebrafish fins, spike cells, and shows their role in maintaining immune cell niche homeostasis through interactions with mpeg1+ immune cells.

This study characterizes the MHC genomic architecture in the Midas cichlid using integrated genomic and transcriptomic analyses, revealing gene diversity, evolutionary patterns, and tissue-specific expression.

The paper maps gene regulators of endothelial cell differentiation using CRISPR and single-cell RNA-seq, identifying Hippo mechanosignaling as critical for endothelial identity.

This study shows that light exposure during rearing induces a developmental switch in zebrafish body color response to light, independent of pineal photoreceptors.

This study maps genome-wide chromatin accessibility in A. calliptera embryos across three stages, revealing dynamic changes in regulatory elements and transcription factor activity during early development.

The paper investigates parasite infections in Nile tilapia aquaculture, finding that monopisthocotylan parasites are prevalent and linked to gill lesions, while stakeholders rarely identify parasites as a health cause.

This paper introduces a new two-photon fluorescence lifetime imaging technique for rapid volumetric imaging of biological samples with high resolution and low phototoxicity.

This study determines cryo-EM structures of FcR bound to IgM and IgA, revealing its binding mechanism and evolutionary insights into pIg receptor recognition.