Pharmaceutical and Antibiotic Environmental Impacts

Responses of Soil Bacterial Community and Its Resistome to Short-term Exposure to Macrolide Antibiotic Macrolactin A: Metagenomic analysis

This study investigates the effects of macrolactin A on soil bacterial communities and ARGs using metagenomic analysis, showing changes in bacterial abundance and resistance gene representation.

Antimicrobial effects, and selection for AMR by non-antibiotic drugs on bacterial communities

This study assesses the antimicrobial effects and AMR selection potential of non-antibiotic drugs on bacterial communities using metagenomic and metatranscriptomic analyses.

A test of long-term and dose-dependent effects of fluoxetine exposure on the velocity of the invasive crayfish Procambarus clarkii

The paper tests long-term and dose-dependent effects of fluoxetine on the dispersal velocity of invasive crayfish, finding a potential decrease in velocity with low-dose exposure over time.

Environmental drivers of the resistome across the Baltic Sea

This study examines how environmental factors shape the resistome in the Baltic Sea, finding that salinity and temperature are key drivers of ARG diversity and distribution.

Suppressing selection for antibiotic resistance in the environment: A transparent, ecology-based approach to predicted no-effect concentrations

The paper proposes an ecology-based method to predict no-effect concentrations for antibiotic resistance using MIC data and fitness cost estimates, suggesting regulatory thresholds should be lowered.

Fish are poor sentinels for surveillance of riverine AMR

This study finds that fish are not effective sentinels for detecting AMR pollution from wastewater treatment plants, as their resistomes do not reflect increases in ARGs in river water and sediment.

Pond Water Microbiome Taxa Profiles and Antibiotic Resistance Genes Associated with Acidity and Tannins

The paper analyzes microbial taxa and antibiotic resistance genes in four ponds, linking their prevalence to environmental factors like pH and tannins.

Genetic compatibility and ecological connectivity drive the dissemination of antibiotic resistance genes

Random forests using nucleotide-composition dissimilarity and metagenomic co-occurrence predict horizontal transfer of resistance genes between bacteria (general model AUROC 0.873); mismatch limits transfer, human and wastewater co-occurrence favors it.

ROS-Induced Stress Promotes Enrichment and Emergence of Antibiotic Resistance in Conventional Activated Sludge Processes

The paper shows that ROS-induced stress in activated sludge processes enriches and promotes the emergence of antibiotic resistance genes, with beta-lactamases and efflux pumps being major contributors.

Jellyfish blooms - an overlooked hotspot and potential vector for the transmission of antimicrobial resistance in marine environments

This study shows that jellyfish blooms create a hotspot for antimicrobial resistance gene (ARG) transmission by promoting microbial growth and horizontal gene transfer in marine environments.

Occurrence, risk assessment of antibiotics and antimicrobial resistance in Escherichia coli in typical rivers of Sichuan

This study assesses antibiotic and antimicrobial resistance in Escherichia coli from Sichuan rivers, finding high contamination and resistance rates, with specific antibiotics linked to ecological risk.

Microbial Metabolic Enzymes, Pathways and Microbial Hosts for Co-Metabolic Degradation of Organic Micropollutants in Wastewater

The paper identifies microbial enzymes, pathways, and hosts involved in co-metabolic degradation of 24 organic micropollutants in wastewater using multi-omics and functional group analysis.

Antibiotic Resistant E. Coli are Common in Waller Creek, an Urban Waterway Chronically Contaminated with Fecal Bacteria

This study examines antibiotic resistance in E. coli from Waller Creek, finding high resistance to ampicillin and erythromycin linked to urbanization and precipitation.

Common non-antibiotic drugs enhance selection for antimicrobial resistance in mixture with ciprofloxacin

This study shows that non-antibiotic drugs enhance the selection of antimicrobial resistance when combined with ciprofloxacin, altering community composition and increasing resistance gene prevalence.

Occurrence of "under-the-radar" antibiotic resistance in anthropogenically affected produce

The paper investigates 'under-the-radar' antibiotic resistance in crops irrigated with treated wastewater and amended with poultry litter, revealing hidden risks through enrichment and molecular techniques.

Antibiotic-resistant bacteria in agricultural soil appraised against non-agricultural soil: case in one of the most agriculturally-active settings in West Cameroon

The paper compares antibiotic-resistant bacteria in agricultural and non-agricultural soils in West Cameroon, finding higher resistance rates in agricultural soils.

Enhanced detection for antibiotic resistance genes in wastewater samples using CRISPR-enriched metagenomic method

This paper develops a CRISPR-enriched metagenomic method to detect antibiotic resistance genes in wastewater, finding it more sensitive than conventional methods.

Hydraulic modelling reveals untreated sewage, not pharmaceutical waste, drives antimicrobial resistance in a small river running through a big city

The paper uses hydraulic modeling and field data to show that untreated sewage, not pharmaceutical waste, is the main source of antimicrobial resistance in the Musi River.

Isolation of a novel Sphingomonas strain able to degrade the pleuromutilin tiamulin: omic analysis reveals its transformation pathway

The paper isolates a novel Sphingomonas strain capable of degrading tiamulin and uses omics analysis to propose a transformation pathway for the antibiotic.

Consumption of Ciprofloxacin as the sole Carbon and energy source and Phenomenal Transformation to a Culturable nanometer-sized- bacterium demonstrated by a hospital-waste-water isolate Klebsiella sp. SG01

This study shows a Klebsiella isolate can degrade ciprofloxacin as its sole carbon source, transforming into a culturable nanobacterium with altered growth and metabolism.

Unexpected levels of antibiotic resistance in marine bacterial communities not solely explained by urban river discharge

The paper investigates antibiotic resistance in marine and freshwater bacterial communities, finding higher resistance in marine environments linked to species diversity rather than urban pollution.

MetaCompare 2.0: Differential ranking of ecological and human health resistome risks

MetaCompare 2.0 differentiates human health and ecological resistome risks using metagenomic data, showing higher risk scores for human-contaminated environments.

The environmental impact of pharmaceuticals: an evidence-mapping review of recent data on aquatic concentrations and predictable effects

This study maps pharmaceutical environmental concentrations and predicted effects, identifying high-risk substances and therapeutic classes globally.

Drivers of antibiotic resistance in two monsoon-impacted Indian urban rivers receiving untreated wastewater

The paper investigates the drivers of antibiotic resistance in two Indian rivers, finding that untreated wastewater is the main source of ARGs rather than heavy metal co-selection.

CIWARS: a web server for waterborne antibiotic resistance surveillance using longitudinal metagenomic data

CIWARS is a web server for analyzing longitudinal metagenomic data to detect antibiotic resistance genes and assess AR risks in environmental samples.

A novel sulfatase for acesulfame degradation in wastewater treatment plants as evidenced from Shinella strains

The paper identifies a novel sulfatase in Shinella strains for acesulfame degradation in wastewater and traces its recent emergence in global wastewater treatment systems.

Metagenomic Insights into the Spatio-temporal Variation of Metal and Antibiotic Resistance Genes in Lake Erie

This study analyzes metagenomic data from Lake Erie to show increased abundance of antibiotic and metal resistance genes over five years.

A Metagenomic Study of Antibiotic Resistance Across Diverse Soil Types and Geographical Locations

This study analyzes antibiotic resistance patterns in soil metagenomes across different types and locations, identifying key resistance genes and their environmental influences.

Microbial Degradation of Contaminants of Emerging Concern by Pseudomonas putida in Wastewater Treatment Plants

This study shows Pseudomonas putida KT2440 can degrade several CECs in lab-scale reactors, with enzyme expression profiles linked to degradation via proteomics and LC-MS/MS.

Environmental antibiotic resistome: selection of HAE-1 efflux pumps in early stages of plant root development

The paper investigates the role of the rhizosphere in selecting HAE-1 efflux pumps in bacterial communities associated with plant roots, showing their enrichment and overexpression in the rhizosphere of older plants.