Salmonella and Campylobacter epidemiology

The paper identifies dual-species interactions between Campylobacter and Enterococcus spp. that confer antibiotic resistance in clinical samples.

The study assesses phenotypic resistance of Campylobacter isolates resistant to azithromycin and ciprofloxacin to additional antibiotics using Kirby-Bauer methods.

The paper compares the intracellular replication of different Salmonella pathovariants in human macrophages, finding that bloodstream-associated variants replicate more efficiently than global epidemic isolates.

The paper analyzes AMR and virulence genes in Salmonella isolates from Africa using multiple databases, finding no correlation between isolate count and AMR prevalence, and identifying meat and dairy as primary sources.

This study uses scRNA-seq to analyze immune cell changes in porcine ileum during Salmonella Typhimurium infection, revealing altered cell composition and immunometabolic responses.

This study shows that SLC11A2 in intestinal epithelial cells restricts iron and manganese to limit Salmonella replication, highlighting its role in nutritional immunity.

This study shows that transient inhibition of T3SS-2 in Salmonella using doxycycline reduces virulence and disease symptoms, with long-term control similar to antibiotics.

The paper characterizes six chimeric plasmids from Salmonella Heidelberg, revealing multidrug resistance and increased pathogenicity through genetic and functional analysis.

This study identifies ancient S. enterica Paratyphi C DNA in 19th-century Mexico, linking it to European strains and showing its persistence in urban settings.

This study develops a multivalent mucosal vaccine using Lactococcus lactis expressing C. jejuni antigens to reduce colonization and modulate gut microbiota in poultry.

This study reconstructs the evolutionary history of ancient Salmonella enterica using 53 new genomes, revealing host adaptation events and convergent evolution in pathogenic lineages.

This study identifies SopB-associated host proteins using Virotrap, revealing SopB's interaction with ESCRT-0 and its role in Salmonella's manipulation of host endosomal trafficking.

This study analyzes Salmonella genomes from African food chains to identify patterns of antimicrobial resistance and quorum sensing, revealing lineage-specific genes and geographic diversity.

This study shows that Campylobacter jejuni in the VBNC state cannot colonize the mouse intestinal tract, suggesting it may not pose a food poisoning risk.

The paper evaluates humoral and cellular immune responses to Salmonella Typhi antigens in typhoid-recovered individuals, finding elevated IgA and TEMRA cells, and comparable IgG and memory B cells between groups.

This study assesses knowledge, attitudes, and biosecurity practices of poultry sellers in Bangladesh to reduce zoonotic salmonellosis risk, finding that education and training significantly influence their practices.

This study identifies how Salmonella uses GLUT1 to access glucose for intracellular growth, revealing a three-step mechanism involving MAPK activation, GLUT1 membrane targeting, and ubiquitination.

This study uses genome minimization and single-cell mass cytometry to identify effector genes in Salmonella that drive pathogen dissemination between immune cells.

This study shows maltose reduces Salmonella Typhimurium's ability to infect epithelial cells by decreasing adhesion through type 1 fimbriae.

This study examines the genomic characteristics and microbiome composition in three cases of Campylobacter and Salmonella co-infections, revealing distinct pathogen strains and microbiome profiles.

This study compares C. jejuni strains causing watery or bloody diarrhea in piglets, finding that bloody strains exhibit greater virulence traits like cell invasion and barrier disruption.

The paper develops a flow cytometry-based method combined with ultra-sensitive proteomics to study host-pathogen interactions in Salmonella-infected macrophages, revealing new insights into virulence factor induction and phagosomal dynamics.

This study compares growth rates and metabolic traits between Campylobacter jejuni strains associated with watery and bloody/inflammatory diarrhea in a neonatal piglet model.

The paper characterizes two Salmonella Typhimurium strains for a first-in-human challenge model, confirming their genomic and phenotypic stability post-manufacture.

This study evaluates stress tolerance in Salmonella enterica strains from foodborne outbreaks and non-outbreaks, finding enhanced tolerance to sanitizers and heat in many isolates.

This study shows that HilE represses motility in typhoidal Salmonella at elevated temperatures, unlike nontyphoidal strains, and this thermoregulation affects host interaction.

This study identifies a small protein, PflE, essential for flagellar assembly and virulence in Campylobacter jejuni by using transposon sequencing in a humanized tissue model.

The paper shows that a diet rich in L-amino acids overrides genetic resistance in mice, promoting Salmonella Typhimurium ileal colonization through microbiota-dependent mechanisms.