Stroke Rehabilitation and Recovery

Electrophysiological Signature of Stroke Recovery: Investigating EEG Biomarkers for Prognostic Insights

This study identifies EEG biomarkers of motor recovery after stroke, finding that changes in relative alpha power and network dynamics explain most of the variance in recovery.

Functional muscle networks reveal the mechanistic effects of post-stroke rehabilitation on motor impairment and therapeutic responsiveness

This study uses a novel muscle network analysis framework to assess post-stroke motor impairment and treatment responsiveness, identifying biomarkers and shifts in muscle coordination associated with recovery.

Scg2 drives reorganization of the corticospinal circuit with spinal premotor interneurons to recover motor function after stroke

This study identifies Scg2 as a secretory protein that promotes axon rewiring and motor recovery after stroke by enhancing axon growth through cAMP and S6 signaling.

Effects of bilateral and unilateral mental practice on actual motor performance and event-related desynchronization

This study examines how bilateral and unilateral mental practice affects motor performance and ERD amplitude, finding that bilateral practice before unilateral practice improves motor performance.

Foot-Ground Force Quantifies Impaired Balance Control Mechanisms Post-Stroke

This study uses computational modeling of foot-ground force data to identify distinct balance control strategies in post-stroke individuals compared to unimpaired adults.

Motor impairment and adaptation in a novel non-human primate model of internal capsule infarct

This study develops a non-human primate model of internal capsule infarct to study motor impairments and adaptations, finding persistent distal deficits and compensatory behavioral strategies.

A Virtual Reality Dataset to Support Hand Action Observation in Rehabilitation and Motor Learning Studies

The paper presents a VR dataset of 33 upper limb gestures for VR-AOT, designed to support standardized and flexible implementation in neurorehabilitation and motor learning.

Insights from multidimensional analyses of post-stroke fatigue

This study investigates post-stroke fatigue by analyzing lesion characteristics and their associations with fatigue facets, revealing links to motor pathways and socio-demographic factors.

Weight-bearing symmetry changes after asymmetric surface stiffness walking

This study investigates asymmetric surface stiffness walking's effects on gait symmetry in healthy adults, finding increased vertical GRF and plantar flexor activity on the perturbed side.

Comparing Robotic and Computer Vision Assessments of Unilateral and Bilateral Reaching in Healthy Adults

This study compares robotic and computer vision methods for assessing unilateral and bilateral reaching in healthy adults, finding differences in performance metrics but consistency with prior research.

Stroke-Related Changes in Tonic and Phasic Muscle Recruitment During Reaching Reveal Pathway-Specific Motor Deficits

This study identifies stroke-related changes in muscle recruitment during reaching by analyzing tonic and phasic EMG components, revealing pathway-specific motor deficits.

Females versus males exhibit greater brain activation in sensorimotor regions during motor imagery after stroke

This study finds sex differences in brain activation during motor imagery after stroke, with females showing greater sensorimotor activation and males greater cerebellar and parietal activation.

Use of the non-paretic arm reflects a habitual behaviour in chronic stroke

This study shows that chronic stroke survivors habitually use their non-paretic arm even when it is less beneficial, especially under time pressure.

Proportional recovery in mice with cortical stroke

This study applies the Proportional Recovery Rule to mice with cortical stroke, finding two recovery clusters and higher recovery in one cluster compared to human studies.

Reinforcement Learning Is Impaired in the Sub-acute Post-stroke Period

This study finds that reinforcement learning is impaired in the sub-acute post-stroke period, while error-based learning remains unaffected, suggesting the need for adjusted rehabilitation strategies.

Identification of distinct subtypes of post-stroke and neurotypical gait behaviors using neural network analysis of kinematic time series data

This paper identifies distinct subtypes of post-stroke and neurotypical gait behaviors using neural network analysis of kinematic time series data, revealing five clusters with unique kinematic patterns.

Impairments in proprioceptively-referenced limb and eye movements in chronic stroke

This study examines how proprioceptive impairments in the upper limb affect eye movement accuracy in stroke survivors, finding a strong correlation between hand and eye proprioceptive errors.

Explicit and implicit locomotor learning in individuals with chronic hemiparetic stroke

This study compares explicit and implicit locomotor learning in individuals with chronic stroke to neurologically intact controls, finding deficits in both processes.

Refined movement analysis in the Staircase test reveals differential motor deficits in mouse models of stroke

The paper uses machine learning to analyze movement in mouse stroke models, revealing distinct motor deficits based on lesion location.

Multi-site identification and generalization of clusters of walking impairment in individuals with chronic stroke and neurotypical controls

The paper identifies and generalizes walking impairment clusters in stroke survivors and controls using spatiotemporal and force data across multiple sites.

Post-Ischemic Reorganization of Sensory Responses in Cerebral Cortex

This study investigates post-ischemic connectivity between premotor and sensory cortex in rats following a primary motor cortex injury, finding evidence of crosstalk and functional recovery.

Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults

This study examines how fast walking affects gait kinematics in stroke survivors compared to neurotypical adults, finding varied biomechanical responses across metrics.

The proportional recovery rule redux: Arguments for its biological and predictive relevance

The paper evaluates the proportional recovery rule (PRR) as a model for motor impairment recovery post-stroke, finding support for its biological relevance and introducing statistical methods to assess recovery models.

Deep learning based behavioral profiling of rodent stroke recovery

This paper develops a deep learning-based method for analyzing rodent stroke recovery using 3D gait tracking and benchmarking against conventional tests.

Increased prevalence of a frontoparietal brain state is associated with better motor recovery in individuals with pontine stroke affecting dominant-hand corticospinal tract

The paper examines brain activity patterns in stroke patients, finding that increased time in a frontoparietal brain state correlates with better motor recovery in those with dominant-hand corticospinal tract damage.

Corpus callosal microstructure predicts bimanual motor performance in chronic stroke survivors: A preliminary cross-sectional study

This study finds that corpus callosum microstructure predicts bimanual motor performance in chronic stroke survivors, with associations beyond primary sensorimotor regions.

Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

This study shows that contralesional excitation after stroke impairs local and global circuit reconnections by suppressing neuroplasticity-related genes.

Chronic stroke sensorimotor impairment is related to smaller hippocampal volumes: An ENIGMA analysis

This study finds that smaller ipsilesional hippocampal volume is associated with worse upper limb sensorimotor impairment in chronic stroke patients, with a stronger effect in women.

Bilaterally Reduced Rolandic Beta Band Activity in Minor Stroke Patients

This study finds that minor stroke patients without significant weakness show reduced rolandic beta band activity in both hemispheres, linked to impaired motor dexterity and processing speed.

Engagement of the contralateral limb can enhance the facilitation of motor output by loud acoustic stimuli

The paper investigates how contralateral limb contractions during action preparation enhance motor output facilitation by loud acoustic stimuli, showing greater facilitation with contralateral low-force flexion contractions.