Topic · Rehabilitation · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
156 papers
Miri Adler, Avi Mayo, Xu Zhou, Ruth A. Franklin, Matthew L. Meizlish, Ruslan M. Medzhitov, Stefan M. Kallenberger, Uri Alon
This study identifies a cell-circuit framework for wound healing and fibrosis, revealing three fibrosis outcomes and parameters that control the transition from healing to fibrosis.
iScience · Jan 16, 2020Peer-reviewedSystems Biology
Martina Balli, Francesca Vitali, Adrian Janiszewski, Ellen Caluwé, Álvaro Cortés-Calabuig, Sébastien Carpentier, Robin Duelen, Flavio Ronzoni, Lukas Marcelis, Francesca Maria Bosisio, Riccardo Bellazzi, Aernout Luttun, Maria Gabriella Cusella De Angelis, Gabriele Ceccarelli, Frederic Lluı́s, Maurilio Sampaolesi
This study shows that autologous micrograft therapy accelerates wound healing by enhancing fibroblast migration through ERK pathway activation and increased matrix metalloproteinase activity.
Cell Death and Differentiation · Oct 25, 2019Peer-reviewedMolecular Biology
Ashley Winn Seifert, Adam B. Cook, Douglas Shaw
This study investigates salamander skin regeneration and development, finding that regeneration follows a developmental pathway distinct from direct development, requiring ECM remodeling and fibroblast activity.
Developmental Biology · Jul 4, 2019Peer-reviewedDevelopmental Biology
Joshua D. Currie, Lidia Grosser, Prayag Murawala, Maritta Schuez, Martin Michel, Elly Margaret Tanaka, Tatiana Sandoval‐Guzmán
This study identifies Prrx1 enhancer-positive dermal fibroblasts as injury-responsive, multipotent cells capable of promoting scar-free wound healing.
bioRxiv · May 3, 2019 · PreprintDevelopmental Biology
Lindsay Kalan, Jacquelyn S. Meisel, Michael A. Loesche, Joseph Horwinski, Ioana Soaita, Xiaoxuan Chen, Sue E. Gardner, Elizabeth A. Grice
This study investigates the role of microbial communities in diabetic foot ulcer healing, finding that strain-level diversity of Staphylococcus aureus and other microbes influence clinical outcomes.
bioRxiv · Sep 27, 2018 · PreprintGenomics
Emanuel Rognoni, Angela Oliveira Pisco, Toru Hiratsuka, Kalle H. Sipilä, Julio Monti Belmonte, Seyedeh Atefeh Mobasseri, Christina Philippeos, Rui Dilão, Fiona M. Watt
The paper shows fibroblast state switching between proliferation and ECM deposition defines dermal architecture and is critical for wound healing.
Molecular Systems Biology · Aug 1, 2018Peer-reviewedSystems Biology