Bacteriophages and microbial interactions

The paper develops an imaging method to map mobile genetic elements and their bacterial hosts in human oral biofilms, revealing spatial clusters of AMR plasmids and prophage.

The paper identifies mutations in phage virion assembly proteins that enable evasion of Type I CBASS immunity by altering infection kinetics.

This study identifies pseudo-pac site sequences in Salmonella genomes that enable P22 phage to initiate generalized transduction, using bioinformatics analysis of sequencing data.

The paper uses microbial single-cell genome sequencing to discover novel endolysins against methicillin-resistant Staphylococcus aureus, identifying a lead endolysin with effective antimicrobial properties.

The paper analyzes the underrepresentation of ESKAPE bacteriophages in public databases and shows its impact on machine learning models.

The paper compiles a global soil virus dataset to assess biodiversity and biogeochemical impacts, finding most viral diversity remains unexplored and viruses may influence carbon and nutrient cycling.

This study identifies and characterizes six new phages targeting uropathogenic Escherichia coli, showing host range correlation with tail fiber proteins and improved efficacy in mixed infections.

This paper describes a truncated endolysin, CHAPSAP26-161, derived from the CHAP domain of LysSAP26, which shows enhanced antibacterial activity and stability against multiple antibiotic-resistant bacteria, including in vivo efficacy against Acinetobacter baumannii.

The paper shows co-infecting phages impede each other's entry into cells, revealing MOI-dependent host physiological changes that affect infection outcomes.

The paper identifies a lipid-based compartment in early phage infection that protects phage DNA and supports early transcription and translation.

The paper studies viral community dynamics on the surface of a French smear-ripened cheese during maturation and across production years, finding persistent dominant phages and shifts in phage-host associations.

The paper identifies a new class of viruses, Mriyaviricetes, with small genomes related to giant Nucleocytoviricota viruses, suggesting they are close relatives of their ancestors and use a unique rolling circle replication mechanism.

This study isolates and characterizes 25 new phages infecting Pseudomonas syringae, revealing genetic diversity and potential auxiliary metabolic genes.

This study demonstrates that phages can bind to seed coat mucilage and enhance plant seedling survival against pathogens, suggesting phage-based biocontrol as a sustainable strategy.

This study shows that temperate and virulent phages affect microbiome diversity and stability differently in simulated ecosystems.

The paper isolates and characterizes 67 phages against Pseudomonas putida, showing their temperature-dependent infectivity, narrow host range, and the role of cryptic prophages in defense.

This study identifies and characterizes two Escherichia coli TAC systems that mediate antiphage defense by recognizing phage proteins and modifying mRNA to inhibit translation.

The paper classifies Lak megaphages into a new viral order, Grandevirales, based on protein and nucleotide analyses, revealing their unique genetic code and evolutionary relationships.

The paper uses protein structure modeling to analyze the evolutionary relationships and functional domains of eukaryotic DNA viruses with double jelly-roll capsids, revealing their origin and evolution.

This study identifies mirusvirus markers in eukaryotic genomes, revealing a broader host range and greater diversity than previously known.

The paper examines soil viral community dynamics over seven years in heated and unheated soils, finding greater spatial variation than temporal changes in viral communities.

The paper tests a bacteriophage cocktail against Klebsiella spp. in vitro and in a Galleria mellonella model, showing it is safe and improves survival.

The paper identifies four protein factors required for LambdaSo phage-induced lysis in Shewanella oneidensis, including a pinholin/SAR-endolysin system and a previously unknown transmembrane protein Lcc6.

This study identifies key traits determining the effectiveness of temperate phages as bacterial weapons and shows how their impact depends on host frequency and environmental factors.

This study investigates the role of the rumen virome in microbial diversification and its association with animal production traits using metagenomic data and network analysis.

This study identifies phage-plasmids in multiple Salmonella serovars, showing their prevalence and serovar-specific distribution, with implications for antimicrobial resistance transmission.

This study identifies 98 novel microvirus genomes from a poultry slaughterhouse, classifies them into 6 new subfamilies and 3 higher-level units, and expands their known host range.

This paper identifies components of a novel protein import pathway in phages, revealing a mechanism for selective protein trafficking into the phage nucleus.

This study deletes Pf prophages from P. aeruginosa isolates and examines their impact on quorum sensing, biofilm formation, and virulence traits.

The paper compares Illumina and Oxford Nanopore sequencing for viral genome recovery from human gut samples, finding Illumina better for resolved genomes and hybrid approaches better for diversity.