Insect Resistance and Genetics

1014F-kdr and G119S ace-1 mutations conferring insecticide resistance detected in the Culex pipiens complex in Morocco

The paper detects two insecticide resistance mutations, L1014F kdr and G119S ace-1R, in Culex pipiens mosquitoes from Morocco, showing varying frequencies and resistance levels between two regions.

Multiplexed amplicon sequencing reveals the heterogeneous spatial distribution of pyrethroid resistance mutations in Aedes albopictus mosquito populations in Southern France.

Structural journey of an insecticidal pore-forming protein targeting western corn rootworm

The paper reveals the molecular mechanism of an insecticidal protein through 3D structures of its three main pore formation states.

Assessing RNAi feasibility and susceptibility to environmental RNAi in Trichogramma dendrolimi (Hymenoptera: Trichogrammatidae)

This study assesses RNAi feasibility and environmental RNAi susceptibility in Trichogramma dendrolimi, finding a complete RNAi pathway and low environmental RNAi sensitivity.

Transcriptome based changes in expression of detoxification genes of Bemisia tabaci under destruxin A treatment

This study investigates the molecular response of Bemisia tabaci to destruxin A treatment using RNA-Seq and identifies detoxification-related genes involved in the defense response.

Intraspecific diversity in the mechanisms underlying abamectin resistance in a cosmopolitan pest

The paper identifies multiple QTLs associated with abamectin resistance in Tetranychus urticae, revealing shared and unique genetic mechanisms across populations.

Chromosome-scale genome assembly of the pink bollworm, Pectinophora gossypiella, a global pest of cotton

The paper presents the first chromosome-level genome assembly of the pink bollworm, providing a complete reference for studying Bt resistance and molecular genetics.

Transcription factor AhR regulates glutathione S-transferases (GSTs) conferring resistance to lambda-cyhalothrin in Cydia pomonella

This study shows that AhR regulates GSTs to confer resistance to lambda-cyhalothrin in Cydia pomonella through induced expression and enzyme activity.

The redlegged earth mite draft genome provides new insights into pesticide resistance evolution and demography in its invasive Australian range

The paper presents the first reference genome of the redlegged earth mite, identifying genes associated with pesticide resistance and population structure in its invasive range.

Emergence of hyper insecticide-resistant dengue vectors in Indochina Peninsula: threats of concomitant knockdown resistance mutations

The paper identifies high-frequency hyper insecticide-resistant mutations in Aedes aegypti from Vietnam and Cambodia, with concomitant mutations showing unprecedented pyrethroid resistance.

Metabolic functional redundancy of the CYP9A subfamily members leads to P450-mediated lambda-cyhalothrin resistance in Cydia pomonella

The paper identifies CYP9A subfamily genes in Cydia pomonella that confer lambda-cyhalothrin resistance through metabolic functional redundancy and regioselectivity.

Functional characterization of cytochrome P450s associated with pyrethroid resistance in the olive fruit fly Bactrocera oleae

The paper identifies P450 enzymes responsible for pyrethroid resistance in Bactrocera oleae by comparing transcriptomes and testing enzyme activity.

Discovery of malathion resistance QTL in Drosophila melanogaster using a bulked phenotyping approach

The paper uses a bulked phenotyping approach to identify QTL associated with malathion resistance in Drosophila melanogaster, finding one QTL implicating Cyp6g1 and another distinct from previous GWAS results.

First report of kdr L1014F and ace-1 G119S insecticide resistance in Belgian Culex (Diptera: Culicidae) mosquitoes

The paper reports the first detection of kdr L1014F and ace-1 G119S insecticide resistance mutations in Belgian Culex mosquitoes, highlighting the need for surveillance.

Multiplex high resolution melting PCR for simultaneous genotyping of pyrethroid-resistance associated mutations in Aedes aegypti. First report on kdr mutations in wild populations from Argentina

The paper develops a high-throughput method for detecting kdr mutations in Aedes aegypti mosquitoes and reports their presence in Argentina for the first time.

A chromosome-scale genome assembly of a Bacillus thuringiensis Cry1Ac insecticidal protein resistant strain of Helicoverpa zea

The paper presents a chromosome-scale genome assembly of a Bt-resistant Helicoverpa zea strain to aid in understanding resistance mechanisms and crop protection strategies.

Abundant trans-driven variation in detoxification gene expression in the extreme generalist herbivore Tetranychus urticae

This study identifies trans-driven expression variation in detoxification genes in Tetranychus urticae, linking it to pesticide resistance and host plant adaptation.

Age-dependent Aedes mosquito resistance profiling and mortality rate to repeated insecticides exposure in Western region, Saudi Arabia

The paper examines age-dependent mortality and genetic resistance in pyrethroid-resistant Aedes aegypti strains after single or repeated insecticide exposure in Saudi Arabia.

Development of efficient RNAi methods in the corn leafhopper Dalbulus maidis, a promising application for pest control

This study evaluates RNAi methods in the corn leafhopper Dalbulus maidis, showing effective gene silencing of BicC via injection and ingestion, with significant phenotypic effects.

Novel genetic basis of resistance to Bt toxin Cry1Ac in Helicoverpa zea

The paper identifies a novel polygenic basis for resistance to Bt toxin Cry1Ac in Helicoverpa zea using genome-wide association and RNA-seq.

Ecdysteroid kinase-like (EcKL) paralogs confer developmental tolerance to caffeine in Drosophila melanogaster

This study identifies EcKL genes in Drosophila melanogaster as detoxification enzymes involved in caffeine and kojic acid tolerance through functional validation and genetic analysis.

Transcriptomic modulation in response to an intoxication with deltamethrin in Triatoma infestans, vector of Chagas disease

This study uses RNA-Seq to analyze the transcriptomic response of Triatoma infestans to deltamethrin, identifying differentially expressed genes and detoxification-related families.

Expansive and diverse phenotypic landscape of field Aedes aegypti larvae with differential susceptibility to temephos: beyond metabolic detoxification

This paper profiles gene expression in temephos-resistant and susceptible Aedes aegypti larvae from two Colombian populations, identifying novel resistance mechanisms beyond metabolic detoxification.

Assessing the Functionality of RNA Interference (RNAi) in the Phloem-feeding Maize pest Dalbulus maidis

This study demonstrates RNAi efficacy in Dalbulus maidis by silencing key genes and inducing mortality, supporting its use in genetic pest control of phloem-feeding insects.

Voltage-sensitive sodium channel (Vssc) mutations associated with pyrethroid insecticide resistance in Aedes aegypti (L.) from Jeddah, Kingdom of Saudi Arabia - baseline information for a Wolbachia release program

This study identifies Vssc mutations associated with pyrethroid resistance in Ae. aegypti from Jeddah, providing baseline data for a Wolbachia release program.

BtToxin_Digger: a comprehensive and high-throughput pipeline for mining toxin protein genes from Bacillus thuringiensis

The paper introduces BtToxin_Digger, a high-throughput pipeline for mining toxin genes from Bacillus thuringiensis genomes and metagenomes, offering improved efficiency and accuracy over previous methods.

High-resolution genetic mapping reveals cis-regulatory and copy number variation in loci associated with cytochrome P450-mediated detoxification in a generalist arthropod pest

This study identifies genetic variants, including copy number variation and cis-regulatory changes, associated with pyflubumide resistance in spider mites through high-resolution genetic mapping and functional experiments.

Detection of alternative splicing in western corn rootworm (Diabrotica virgifera virgifera LeConte) in association with Bt resistance using RNA-seq and PacBio Iso-Seq

The paper identifies alternative splicing events in western corn rootworm midguts in response to Bt toxin exposure using RNA-seq and PacBio Iso-Seq.

Engineered expression of the invertebrate-specific scorpion toxin AaHIT reduces adult longevity and female fecundity in the diamondback moth Plutella xylostella

This paper shows that expressing the scorpion toxin AaHIT in diamondback moth reduces adult lifespan and female egg production, demonstrating a non-cell-autonomous genetic pest management approach.

Intron-assisted, viroid-based production of insecticidal circular double-stranded RNA in Escherichia coli

This paper describes a system for producing insecticidal circular dsRNA in E. coli using viroid scaffolds and introns, demonstrating its effectiveness against Western corn rootworm.