Animal Disease Management and Epidemiology

Interactions between the 2C protein of FMDV and components of the viral replication machinery are mediated by ER-derived membranes

This study identifies interactions between FMDV 2C protein and viral and host factors, revealing ER-derived replication complexes and potential targets for disrupting the FMDV lifecycle.

Machine learning approaches for estimating cross-neutralization potential among FMD serotype O viruses

This paper develops a machine learning model to predict cross-neutralization potential between FMDV serotype O viruses using sequence data and identifies key genomic predictors.

Modelling PRRS transmission between pig herds in Denmark and prediction of interventions impact

This paper models PRRS transmission between pig herds in Denmark and evaluates the impact of control interventions, finding that undetected herds drive most transmission and eradication requires multiple strategies.

Wild boar trade and African swine fever risk of introduction into new territories: A quantitative release assessment with retrospective data of wild boar shipments to France and Spain (2010-2017).

This study assesses the risk of African swine fever introduction through wild boar trade to France and Spain (2010-2017) and supports the 2018 EU trade ban.

ANASFV: a workflow for ASFV whole genome sequencing, assembly, and evaluation

The paper develops ANASFV, a pipeline for ASFV whole genome sequencing, assembly, and evaluation, addressing challenges like contamination, error rates, and recombination analysis.

Rapid spread of African Swine Fever across Borneo

This study tracks the rapid spread of African Swine Fever across Borneo using citizen science data and estimates the increasing speed of the virus's spread.

Investigating the impact of edge weight selection on the pig trade network topology

The paper evaluates how edge weight selection affects node ranking in a pig trade network, showing that strength centrality improves surveillance strategies by identifying critical holdings.

Targeted Whole Genome Sequencing of African Swine Fever Virus and Classical Swine Fever Virus on the MinION Portable Sequencing Platform

This study develops targeted whole genome sequencing protocols for ASFV and CSFV using MinION sequencing to enable rapid and complete genetic characterization of outbreak strains.

Evaluation of Aggregate Oral Fluid Sampling for Early Detection of African Swine Fever Virus Infection

This study evaluates aggregate oral fluid sampling for early detection of African swine fever virus in pigs, showing it can detect ASFV as early as 3 days post-contact.

Climate warming drives pulsed-resources and disease outbreak risk

The paper explores how climate warming affects disease outbreak risk by considering both direct and indirect effects on host and pathogen dynamics in wild boars.

Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape

The paper evaluates vaccination strategies for Rift Valley fever in the Comoros archipelago, finding that optimal allocation improves effectiveness but creates inequity, while animal tagging enhances outcomes across all rates.

Exploring virus-host interactions through combined proteomic approaches identifies BANF1 as a new essential factor for African Swine Fever Virus.

This study identifies BANF1 as a host factor essential for ASFV replication and reveals that A151R and MGF360-21R inhibit the IFN-I response, independent of BANF1.

Bovine tuberculosis model validation against a field study of badger vaccination with selective culling

The paper validates a bovine tuberculosis model against a field study of badger vaccination with selective culling, showing similar outcomes when social perturbation is excluded.

Allocating Limited Surveillance Effort for Outbreak Detection of Endemic Foot and Mouth Disease

This study evaluates three sentinel surveillance strategies for detecting FMD outbreaks in Turkey, finding that all methods detect more outbreaks than random sampling, with spatial and network connectivity methods performing similarly.

Evaluating the effect of badger culling on TB incidence in cattle: a critique of Langton et al. 2022

This paper critiques Langton et al. 2022's analysis of badger culling's effect on cattle TB, identifying methodological flaws and demonstrating how their approach may lead to incorrect conclusions.

Membrane Expression Enhances Folding, Multimeric Structure Formation, and Immunogenicity of Viral Capsid Proteins

This study enhances the immunogenicity of viral capsid proteins by engineering them into membrane-bound or secreted forms, showing improved folding and T cell responses in animal models.

Evaluating the antiviral activity of Termin-8 and Finio against a surrogate ASFV-like algal virus

This study evaluates the antiviral activity of Termin-8 and Finio against the algal virus EhV, showing both products reduce viral load, with Finio achieving greater inactivation.

Serosurveillance Studies of Peste des Petits Ruminants (PPR) Virus in Sheep and Goats in South Asia: A Systematic Review and Meta-analysis

This study conducts a systematic review and meta-analysis to estimate the pooled seroprevalence of PPRV in sheep and goats in South Asia, finding 42.4% overall prevalence with variations by country and vaccination status.

Early disruption of the innate-adaptive immune axis in vivo after infection with virulent Georgia2007/1 ASFV

This study examines immune dynamics in pigs infected with virulent ASFV, finding early disruption of the innate-adaptive immune axis and depletion of adaptive immune cells.

Selection, Design and Immunogenicity Studies of ASFV Antigens for Subunit mRNA Cocktail Vaccines with Specific Immune Response Profiles

The paper selects and evaluates ASFV antigens for subunit mRNA vaccines, showing divergent immune responses and developing a computational method to design antigen cocktails.

Integrating Behavioural Science and Epidemiology to Improve Early Detection of Zoonotic Swine Influenza in the Netherlands

The paper develops a framework integrating behavioural science and epidemiology to improve early detection of zoonotic swine influenza by simulating farmer responses and disease spread.

Modeling the transmission dynamics of African swine fever virus within commercial swine barns: Quantifying the contribution of multiple transmission pathways

This study models ASFV transmission within swine barns, identifying between-pen contact as the primary route, with nose-to-nose contact contributing most, and aerosol transmission having minimal impact.

Evaluation of porcine epidemic diarrhea virus RNA contamination on swine industry transportation vehicles

This study evaluates PEDV RNA contamination on swine transportation vehicles before and after cleaning, finding pigs-to-market trucks are most contaminated and quaternary ammonium/glutaraldehyde disinfectants are more effective.

An Update on Active and Passive Surveillance for African Swine Fever in the Dominican Republic

This study assesses the distribution and control of African Swine Fever in the Dominican Republic using surveillance data from 2023-2024, finding a stable state with low attack rates and an R0 near 1.

Identifying control strategies to eliminate African swine fever from the United States swine industry in under 12 months

This paper uses a mathematical model to identify intensified control strategies needed to eliminate African swine fever from U.S. swine populations within 12 months.

The pseudoknot region and poly-(C) tract comprise an essential RNA packaging signal for assembly of foot-and-mouth disease virus

This study identifies the pseudoknot region and poly-(C) tract as essential RNA packaging signals for foot-and-mouth disease virus (FMDV) assembly, showing that their length and interactions influence packaging efficiency.

Simulating the diffusion of PPR-like disease to improve surveillanc

The paper simulates the spread of a PPR-like disease using mobility data to identify sentinel nodes and assess the impact of missing movement data on epidemic prediction.

Assessing the impact of structural modifications in the construction of surveillance network for transboundary animal diseases: the role of backbone and sentinel nodes

The paper identifies sentinel nodes in Nigeria's livestock movement network to improve PPR surveillance, finding 45% of backbone nodes remain stable across configurations.

Spatial distribution of poultry farms using point pattern modelling: a method to address livestock environmental impacts and disease transmission risks

This paper develops a farm distribution model to predict poultry farm locations and sizes in data-scarce regions, showing that spatial clustering increases disease transmission risk.

Estimating sampling and laboratory capacity for a simulated African swine fever outbreak in the United States

This study models the resource requirements for detecting an ASFV outbreak in the U.S., finding that sample collectors and lab capacity are critical to prevent delays.