Exercise and Physiological Responses

Exercise training at different intensities induces heat stress, disrupts barrier function and alters microbiota in the gut of mice

This study compares the effects of moderate and vigorous exercise on intestinal damage, stress response, inflammation, and gut microbiota in mice, finding that daily moderate exercise causes more severe injury than vigorous training with rest days.

No effect of menstrual cycle phase on eccentric exercise-induced neuromuscular impairments and the magnitude of the repeated bout effect

This study found no effect of menstrual cycle phase or oral contraceptive use on neuromuscular impairments after eccentric exercise or the repeated bout effect.

Organism-wide secretome mapping uncovers pathways of tissue crosstalk in exercise

This study maps the organism-wide secretome response to exercise in mice, identifying 200+ exercise-regulated protein pairs and uncovering anti-obesity and anti-diabetic roles of a liver-secreted proteoform.

Temporal dynamics of the multi-omic response to endurance exercise training across tissues

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.

Dynamic Transcriptomic Network Responses to Divergent Acute Exercise Challenges in Young Adults

The paper compares transcriptomic responses in skeletal muscle and extracellular vesicles after traditional and high-intensity exercise in young adults, finding more consistent gene responses to traditional exercise and unique microRNA responses to high-intensity training.

Molecular Choreography of Acute Exercise

The paper characterizes the dynamic multi-omic molecular response to acute exercise and identifies biomarkers of fitness.

Decreased integrity of exercise-induced plasma cell free nuclear DNA - negative association with the increased oxidants production by circulating phagocytes

The paper examines how strenuous exercise affects plasma cell free nuclear DNA integrity and its link to oxidant production by phagocytes.

Exercise conditioned plasma dampens inflammation via clusterin and boosts memory

The paper shows that plasma from exercising mice reduces brain inflammation and improves memory, with clusterin as a key anti-inflammatory factor also elevated in human exercisers.